Understanding Transformer-Based Classifications of Medical Text Using a Large Language Model for the Attribution of Feature Importance: Proof-of-Concept Algorithm Development and Validation Study. [PDF]
Zhou F +6 more
europepmc +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Correction to: Simultaneous prediction of early and delayed mortality in burn patients: a comparative machine learning analysis of feature importance in a single-center retrospective study. [PDF]
Motamedi M +4 more
europepmc +1 more source
Inferring feature importance with uncertainties with application to large genotype data. [PDF]
Johnsen PV +4 more
europepmc +1 more source
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley +1 more source
A comprehensive feature importance analysis of surgical site infection following colorectal cancer surgery. [PDF]
Rahimi M +7 more
europepmc +1 more source
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Integrating feature importance techniques and causal inference to enhance early detection of heart disease. [PDF]
Arzanipour A.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

