Results 91 to 100 of about 2,188,827 (291)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
GeoAT: Geometry-Aware Attention Feature Matching Network
IEEE AccessAttention mechanisms have achieved remarkable success in the field of computer vision. However, in the context of image matching with large deformations, attention often suffers from divergence issues.
Yan Li +4 more
doaj +1 more source
Scale‐invariant feature matching based on pairs of feature points
IET Computer Vision, 2015 On the basis of feature points pairing, a scale‐invariant feature matching method is proposed in this study. The distance between two features is used to compute feature pairs' support region size, which is different from the methods using detectors to ...
Zhiheng Wang +3 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A study of stereo microscope measurements based on interpolated feature matching
, 2015 Recently, digital stereo microscopes have been becoming increasingly popular in fields such as biomedicine and biotechnology. As such, being able to precisely match left/right feature pairs is critical, which is an important step in stereo matching.
Deng, Jing +4 more
core
Laser scan matching using multiplex histograms with feature components
, 2009 A new laser scan matching algorithm is proposed in this paper. By constructing multiplex histograms, the new algorithm offers a simple way for importing geometrical features into the histogram method, obtaining more geometrical information from the laser
Quan Qiu +3 more
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Matching Multi-Source Optical Satellite Imagery Exploiting a Multi-Stage Approach
Remote Sensing, 2017 Geometric distortions and intensity differences always exist in multi-source optical satellite imagery, seriously reducing the similarity between images, making it difficult to obtain adequate, accurate, stable, and well-distributed matches for image ...
Yuxuan Liu, Fan Mo, Pengjie Tao
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source