Results 131 to 140 of about 3,367,886 (347)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Matching Multi-Source Optical Satellite Imagery Exploiting a Multi-Stage Approach
Geometric distortions and intensity differences always exist in multi-source optical satellite imagery, seriously reducing the similarity between images, making it difficult to obtain adequate, accurate, stable, and well-distributed matches for image ...
Yuxuan Liu, Fan Mo, Pengjie Tao
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Slope-Restricted Multi-Scale Feature Matching for Geostationary Satellite Remote Sensing Images
For geostationary meteorological satellite (GSMS) remote sensing image registration, high computational cost and matching error are the two main challenging problems.
Dan Zeng +3 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Scale‐invariant feature matching based on pairs of feature points
On the basis of feature points pairing, a scale‐invariant feature matching method is proposed in this study. The distance between two features is used to compute feature pairs' support region size, which is different from the methods using detectors to ...
Zhiheng Wang +3 more
doaj +1 more source
Feature Based Particle Filter Registration of 3D Surface Models and its Application in Robotics
This work is focused on global registration of surface models such as homogeneous triangle meshes and point clouds. The investigated approach utilizes feature descriptors in order to assign correspondences between the data sets and to reduce complexity ...
Michael Suppa +9 more
core +1 more source
We propose a feature-oriented ensemble history-matching workflow with a focus on the integration of time-lapse seismic and electromagnetic (EM) data. The developed workflow consists of two main steps.
Hoteit, Ibrahim, Zhang, Yanhui
core +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source

