Results 151 to 160 of about 3,367,886 (347)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
GPU Accelerated Processing Method for Feature Point Extraction and Matching in Satellite SAR Images
Applied SciencesThis paper addresses the challenge of extracting feature points and image matching in Synthetic Aperture Radar (SAR) satellite images, particularly focusing on large-scale embedding.
Lei Dong +4 more
doaj +1 more source
A star image registration algorithm based on joint feature matching
, 2017 With the amount of space debris increasing accordingly with human activities in near space, the threat of space debris to space missions raises the concern of surveillance of these malicious targets.
Zhao Li, Li, Zhao, Yan Wen, Wen, Yan
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Automatic Landmarking for Non-cooperative 3D Face Recognition [PDF]
, 2011 This thesis describes a new framework for 3D surface landmarking and evaluates its performance for feature localisation on human faces. This framework has two main parts that can be designed and optimised independently.
Creusot, Clement, Clement Creusot
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
ICA-ASIFT-Based Multi-Temporal Matching of High-Resolution Remote Sensing Urban Images
Cybernetics and Information Technologies, 2016 While SIFT (Scale Invariant Feature Transform) features are used to match High-Resolution (HR) remote sensing urban images captured at different phases with large scale and view variations, feature points are few and the matching accuracy is low ...
Huang Fenghua, Mao Zhengyuan, Shi Wenzao
doaj +1 more source
View synthesis for kinetic depth X-ray imaging
, 2012 This thesis reports the development and analysis of feature based synthesis of transmission X-ray images. The synthetic imagery is formed through matching and morphing or warping line-scan format images produced by a novel multi-view X-ray machine.
Abusaeeda, OA
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source