Results 131 to 140 of about 195,131 (299)

/h/ insertion as a 'camouflaged archaism'?: dialect contact, colonial lag and the feature pool in South Atlantic English.

open access: yes, 2019
This article documents the historical development and synchronic variation of so-called “/h/ insertion” (/h/ before vowel-initial words such as apple, under, etc.). It argues that the maintenance of /h/ insertion in post-colonial English varieties around
Schreier, Daniel; https://orcid.org/   +1 more
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

A Single Tropical Rainbelt in Global Storm‐Resolving Models: The Role of Surface Heat Fluxes Over the Warm Pool

open access: yesJournal of Advances in Modeling Earth Systems
Global uncoupled storm‐resolving simulations using the ICOsahedral Non‐hydrostatic (ICON) model with prescribed sea surface temperature (SST) show a double band of precipitation in the Western Pacific, a feature explained by reduced precipitation over ...
H. Segura   +13 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

FEATURE SELECTION FOR TOOL WEAR DIAGNOSIS USING SOFT COMPUTING TECHNIQUES

open access: yes, 2008
– This paper examines feature selection methods in the context of milling machine tool wear diagnosis. Given raw sensor signals acquired during experiments, a pool of features was created through calculation by several feature extraction methods.
Kai Goebel
core  

A Pool Drowning Detection Model Based on Improved YOLO

open access: yes
Drowning constitutes the leading cause of injury-related fatalities among adolescents. In swimming pool environments, traditional manual surveillance exhibits limitations, while existing technologies suffer from poor adaptability of wearable devices ...
Wenhui Zhang, Lu Chen, Jianchun Shi
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Step down logistic regression for feature selection

open access: yes, 1997
This paper proposes a methodology to the feature selection problem of pattern classification problems. For this purpose, pattern recognition or signal processing involves two major tasks: clustering transformation and then, feature selection. The concept
Baykal, Nazife
core  

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