Results 121 to 130 of about 1,793,798 (289)
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Should you believe in the Shanghai ranking? [PDF]
This paper proposes a critical analysis of the "Academic Ranking of World Universities", published every year by the Institute of Higher Education of the Jiao Tong University in Shanghai and more commonly known as the Shanghai ranking.
Denis Bouyssou +2 more
core
Applied SciencesFeature selection is one of the key stages in the process of creating machine learning models and conducting data analysis. This paper presents the results of research related to the implementation of a new algorithm for feature selection and ranking ...
Aleksander Wojtowicz +2 more
doaj +1 more source
Feature Ranking by Variational Dropout for Classification Using Thermograms from Diabetic Foot Ulcers. [PDF]
Sensors (Basel), 2023 Hernandez-Guedes A +4 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Attribute Relevance Score: A Novel Measure for Identifying Attribute Importance
AlgorithmsThis study introduces a novel measure for evaluating attribute relevance, specifically designed to accurately identify attributes that are intrinsically related to a phenomenon, while being sensitive to the asymmetry of those relationships and noise ...
Pablo Neirz +2 more
doaj +1 more source
Feature Signature Discovery for Autism Detection: An Automated Machine Learning Based Feature Ranking Framework. [PDF]
Comput Intell Neurosci, 2023 Jacob SG, Sulaiman MMBA, Bennet B.
europepmc +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source