Results 121 to 130 of about 1,151,147 (311)

Investigation of Some Performance Characteristics and Handball Talent Levels of Male and Female Students

open access: yesTürk Spor ve Egzersiz Dergisi, 2018
In this study, it was aimed to determine the performance characteristics and skill levels specific to the sport branch and to determine the talent and to direct the correct branch while the children with very high potential in our country are directed to
İdris Kayantaş   +3 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Analysis of features selection for p2p traffic detection using support vector machine

open access: yes, 2013
Network traffic classification plays a vital role in various network activities. Network traffic data include a large number of relevant and redundant features, which increase the flow classifier computational complexity and affect the classification ...
Zarei, Roozbeh   +11 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Dimensionality Reduction Through Unsupervised Features Selection

open access: yes, 2007
As the storage technologies evolve, the amount of available data explodes in both dimensions: samples number and input space dimension. Therefore, one needs dimension reduction techniques to explore and to analyse his huge data sets.
Guérif, Sébastien   +3 more
core  

Rolling Bearing Fault Diagnosis Using Modified Neighborhood Preserving Embedding and Maximal Overlap Discrete Wavelet Packet Transform with Sensitive Features Selection

open access: yes, 2018
In order to enhance the performance of bearing fault diagnosis and classification, features extraction and features dimensionality reduction have become more important. The original statistical feature set was calculated from single branch reconstruction
Fei Dong   +5 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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