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The TH1/TH2 Response Imbalance Zika Virus Pathogenesis: An Immunological Paradox

APMIS, Volume 133, Issue 12, December 2025.
ABSTRACT Since its identification in 1947 and its global emergence in the Americas decades later, the Zika virus (ZIKV) has proven to be a multifaceted challenge to public health. Among the many aspects that remain poorly understood, the complex immunological paradox between Th1 and Th2 responses stands out, playing a central role in the ...
Carla Menezes +6 more
wiley +1 more source

Global anaesthesia practice using inguinal hernia surgery as a tracer condition: a secondary analysis of an international prospective cohort study

Anaesthesia, Volume 80, Issue 11, Page 1343-1351, November 2025.
Summary Introduction Restoration of surgical capacity is essential to post‐COVID‐19 recovery. This study explored the use and safety of anaesthesia options for inguinal hernia surgery, a common tracer condition, to describe current global practice and highlight opportunities to build the capacity of health systems.
NIHR Global Health Research Group on Environmentally Sustainable Hospitals in Low‐ and Middle‐income Countries +5007 more
wiley +1 more source

Loss of MTAP expression is not an accurate surrogate for CDKN2A homozygous deletions in peritoneal mesothelioma

Histopathology, Volume 87, Issue 4, Page 526-535, October 2025.
MTAP immunohistochemistry (IHC) was evaluated as a diagnostic tool for peritoneal mesothelioma by comparing it with CDKN2A homozygous deletion (HD) detected by FISH. Results showed low concordance between MTAP IHC and CDKN2A HD, suggesting MTAP IHC is not reliable for predicting CDKN2A HD in peritoneal mesothelioma. Further studies are needed.
Andrea Quaranta +14 more
wiley +1 more source

Febre e adenopatias em mulher jovem de raça negra – caso clínico

Galicia Clínica, 2014
A doença de Kikuchi, também designada linfadenite histiocítica necrotizante, é uma doença rara, autolimitada e de etiologia ainda não esclarecida. A maioria dos casos descritos são em doentes de origem asiática, sendo muito raros os casos em doentes de ...
doaj +1 more source

Crystal structure of the sucrose phosphorylase from Alteromonas mediterranea shows a loop transition in the active site

Acta Crystallographica Section F, Volume 81, Issue 7, Page 306-310, July 2025.
Sucrose phosphorylases catalyse a bi‐bi reaction that interconverts sucrose and phosphate into glucose α‐1‐phosphate and fructose. Here, we present the first crystal structure of a sucrose phosphorylase from a marine organism.Sucrose phosphorylases are essential enzymes regulating sucrose metabolism, and it has been shown that a loop rearrangement is ...
Folmer Fredslund +6 more
wiley +1 more source

Meningoencefalite causada pelo vírus vacinal da febre amarela transmitido pelo leite materno

Jornal de Pediatria, 2011
OBJETIVO: Relatar um caso de meningoencefalite, provavelmente causada pelo vírus vacinal da febre amarela transmitido pelo leite materno. DESCRIÇÃO: Paciente de 38 dias de idade, internado em 23/05/09 para investigação de febre. No dia 25/05/09 iniciaram-
Cristiane Traiber +3 more
doaj +1 more source

Uncertainty‐aware fuzzy knowledge embedding method for generalized structural performance prediction

Computer-Aided Civil and Infrastructure Engineering, Volume 40, Issue 17, Page 2546-2560, 14 July 2025.
Abstract Structural performance prediction for structures and their components is a critical issue for ensuring the safety of civil engineering structures. Thus, enhancing the reliability of the prediction models with better generalization capability and quantifying the uncertainties of their predictions is significant.
Xiang‐Yu Wang, Xin‐Rui Ma, Shi‐Zhi Chen +2 more
wiley +1 more source

Comfort in Providing Care and Associations With Attitudes Towards Substance Use: A Survey of Mental Health Clinicians at an Urban Hospital in Vancouver, Canada

Journal of Psychiatric and Mental Health Nursing, Volume 32, Issue 3, Page 774-782, June 2025.
ABSTRACT Introduction Stigma is a major driver of harms associated with substance use and can interfere with the provision of high‐quality, effective healthcare for people who use drugs. Our study aimed to explore the relationship between mental health clinicians' comfort in providing substance use care and their attitudes towards substance use ...
Angela Russolillo +4 more
wiley +1 more source

Febre feminista

MODOS: Revista de História da Arte, 2023
É possível verificar que já há cerca de seis/sete anos no Brasil vive-se uma febre midiática do feminismo em sua multiplicidade de abordagens e agendas. Especificadamente no campo da cultura, ou melhor, no sistema das artes, esse período proporcionou uma onda de exposições em artes visuais, de pequeno a grande porte, em grandes centros artísticos e ...
openaire +1 more source

Graft union formation involves interactions among bud signals, carbon availability, dormancy release, wound responses and non‐self‐communication in grapevine

The Plant Journal, Volume 122, Issue 5, June 2025.
Significance Statement Grafting is essential to the cultivation of many perennial fruit crops, but we have little understanding of the processes involved. Here, we identify wounding and grafting‐specific gene expression and metabolite accumulation profiles and identify some of the factors regulating these changes. SUMMARY Grafting plants uses intrinsic
Grégoire Loupit +11 more
wiley +1 more source

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