Results 111 to 120 of about 1,515 (213)
Bridging the Gap Between General and Transplant Infectious Disease Practice
ABSTRACT The population of iatrogenic immunocompromised individuals is steadily rising as we continue to improve in our ability to manage diseases, including cancer, autoimmune disease, and end‐organ dysfunction, with increasing access to novel agents and transplantation.
Jeremey Walker +4 more
wiley +1 more source
ABSTRACT Objective Scrub typhus is a major cause of acute undifferentiated febrile illness (AUFI) in the Asia–Pacific region. Nonspecific presentation, limited diagnostic accuracy and delayed treatment increase morbidity and mortality. This study aimed to develop a simple clinical score for early diagnosis in adults with AUFI. Methods A cross‐sectional
Wilawan Thipmontree +3 more
wiley +1 more source
Thalassemia major may decrease the frequency of febrile convulsions in children
Aim: We aimed to determine the relative frequency of febrile convulsion in children with major thalassemia to theorize that higher serum iron levels could reduce the incidence of febrile convulsion.
Malamiri, Reza Azizi +3 more
core +1 more source
ABSTRACT Background Acute febrile illnesses in sub‐Saharan Africa are often attributed to malaria, yet many patients test negative for malaria parasites. The aetiology of nonmalarial fevers remains understudied. Here, we examine likely causes of febrile illnesses and their association with poor clinical outcomes in Angola.
Helga E. M. Gonçalves +3 more
wiley +1 more source
Background and objective: The most prevalent cause of convulsions in young children is febrile convulsions. The ratio of neutrophils to lymphocytes (NLR), the mean platelet volume (MPV), and the platelet count are indicators of inflammation.
Sherzad A. Mosa +3 more
doaj +1 more source
Bacterial screening of platelet donations in England, 2014–2023
Abstract Background and Objectives Bacterial contamination of blood components is an ongoing problem in transfusion medicine. We analysed the bacterial screening data of platelets from England, 2014–2023, and compared this with data on reported near‐misses and transfusion‐transmitted infections (TTIs). Materials and Methods Anonymized data on bacterial
Vidushi Chugh +6 more
wiley +1 more source
ABSTRACT Optimal cephalexin and cefadroxil dosing for skin and soft tissue infections (SSTIs) is unclear. We summarize clinical and pharmacokinetic/pharmacodynamic (PK/PD) data that compare dosing strategies for SSTIs. Additionally, we conduct population PK target attainment simulations for varying doses of cephalexin and cefadroxil for Staphylococcus ...
Jonathan H. Ryder +6 more
wiley +1 more source
Improved Detection and Sequencing of Rickettsia spp. DNA in South African Wildlife
Nested gltA PCR detected Rickettsia spp. DNA in 44% of South African wildlife samples previously negative by RLB, revealing spotted fever, typhus and transitional group lineages, novel host records, co‐infection and multi‐organ dissemination in impala, highlighting complex wildlife involvement and zoonotic risk within a One Health framework.
Carlo Andrea Cossu +5 more
wiley +1 more source
ABSTRACT Relapsed and refractory multiple myeloma (RRMM) remains associated with poor outcomes, particularly in patients exposed or refractory to proteasome inhibitors, immunomodulatory agents, and anti‐CD38 monoclonal antibodies. Targeting B‐cell maturation antigen (BCMA) has emerged as an effective therapeutic strategy, prompting the development of ...
Maria Eugenia Alvaro +12 more
wiley +1 more source
ABSTRACT Acute lymphoblastic leukaemia (ALL) in older adults represents a growing clinical challenge, driven by an ageing population, adverse disease biology, and reduced tolerance to intensive chemotherapy. Although pediatric‐inspired regimens have improved outcomes in younger adults with Philadelphia chromosome (Ph)‐negative ALL, survival in older ...
Antonella Bruzzese +12 more
wiley +1 more source

