Results 41 to 50 of about 31,918 (237)

Efficacy and safety of fruquintinib combined with albumin‐bound paclitaxel as second‐line therapy for advanced gastric cancer following failure of PD‐1 inhibitor‐containing treatment (TACTIC GC‐01): A phase II single‐arm study

International Journal of Cancer, EarlyView.
What's New? Anti‐angiogenic drugs have shown promising efficacy as a second‐line treatment for advanced gastric cancer. However, it remains unclear how alterations in the tumor microenvironment following first‐line immunotherapy may impact tumor angiogenesis and influence subsequent therapeutic outcomes. This single‐arm study prospectively explored the
Xiaoting Ma, Kai Ou, Xiu Liu, Biyang Cao, Wenwei Yang, Jingyu Lu, Letian Zhang, Qi Wang, Lizhen Gao, Zhichao Jiang, Yongkun Sun, Lin Yang   +11 more
wiley   +1 more source

Clinical trial of safety and antitumor activity of farletuzumab ecteribulin in patients with platinum‐resistant ovarian cancer: Phase I expansion results

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori, Mayu Yunokawa, Koji Matsumoto, Kazuhiro Takehara, Kosei Hasegawa, Yasuyuki Hirashima, Hidenori Kato, Hiroki Ikezawa, Yohei Otake, Wataru Yusa, Takuma Miura, Shin Nishio   +11 more
wiley   +1 more source

Testicular Abscess an Unusual Cause for Febrile Neutropenia

The Scientific World Journal, 2008
Patients with good-risk disseminated testicular cancer are effectively managed with platinum-based chemotherapy. Febrile neutropenia is a dose-limiting event for many chemotherapy regimens.
Tal Grenader
doaj   +1 more source

Triagem para o tratamento ambulatorial da neutropenia febril Screening for the outpatient treatment of febrile neutropenia

Revista Brasileira de Hematologia e Hemoterapia, 2010
A neutropenia febril (NF) é uma complicação frequente e potencialmente fatal nos pacientes em tratamento quimioterápico. Entendemos hoje que a neutropenia febril é considerada uma emergência clínica e que a administração de antibióticos de amplo espectro
Marcelo Bellesso, Silvia Figueiredo Costa, Dalton Alencar Fischer Chamone, Pedro Enrique Dorlhiac Llacer   +3 more
doaj   +1 more source

Neoadjuvant Chemotherapy With Gemcitabine/Cisplatin/S‐1 for Resectable Biliary Tract Cancer With FDG‐PET‐Positive Lymph Node Metastasis (KHBO1201): A Multicenter Phase II Trial

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Purpose To evaluate the safety and efficacy of neoadjuvant gemcitabine, cisplatin, and S‐1 (GCS) chemotherapy for resectable biliary tract cancer (BTC) and FDG‐PET‐positive lymph nodes in a multicenter phase II study (KHBO1201). Methods Patients with resectable BTC (intrahepatic/extrahepatic bile duct, gallbladder, or ampullary cancers) and ...
Satoshi Ogiso, Etsuro Hatano, Satoru Seo, Masashi Kanai, Shogo Kobayashi, Hiroshi Wada, Hidetoshi Eguchi, Tatsuya Higashi, Hiroaki Nagano, Tatsuya Ioka   +9 more
wiley   +1 more source

Composite Adverse Event Outcome in Pediatric Cancer Patients with Prolonged Febrile Neutropenia [PDF]

Journal of Microbiology and Infectious Diseases, 2016
Objective: Pediatric cancer patients with prolonged febrile neutropenia have increased risk for severe, recurrent or new bacterial and fungal infection.
Muhammad Matloob Alam
doaj   +1 more source

Global Emergency Medicine: A Scoping Review of the Literature From 2024

Academic Emergency Medicine, EarlyView.
ABSTRACT Objective The Global Emergency Medicine Literature Review (GEMLR) identifies impactful research in global emergency care. This 20th annual edition reviews GEM literature published in 2024 and highlights the growth of GEMLR over the years. Methods We conducted a scoping review of 2024 GEM articles through structured PubMed and gray literature ...
J. Austin Lee, Nana Serwaa A. Quao, Amanda Collier, Chris A. Rees, Morgan C. Broccoli, Nanaba A. Dawson‐Amoah, Vinay N. Kampalath, Joseph Ciano, Ashley Jacobson, Jennifer Jones, Joseph Leanza, Branden Skarpiak, Jonathan M. Strong, Braden J. Hexom, Global Emergency Medicine Literature Review (GEMLR) Group, Abdirahman Abdulle, Halley J. Alberts, Kimonia Bih Awanchiri, Emily Bartlett, Tal Berkowitz, Nidhi Bhaskar, Corey B. Bills, Joseph Bonney, Morgan C. Broccoli, Agatha Brzezinski, Whitney K. Bryant, Jonathan Chan, Joseph D. Ciano, Cassandra Clay, Ly Cloessner, Amanda Collier, Nanaba A. Dawson‐Amoah, Kamoga Dickson, Jonathan W. Dyal, Christian Engelen, Brandon Friedman, Stephanie Chow Garbern, Juliette Gerardo, Mindi Guptill, Reid Haflich, Alison S. Hayward, Braden J. Hexom, Taylor S. Hickey, Anneka Hooft, Emmanuel Oluyinka Idowu, Ashley A. Jacobson, Aqeel Jawahir, Jennifer E. Jones, Vinay N. Kampalath, Elizabeth M. Keating, Sean M. Kivlehan, Arthi S. Kozhumam, Colleen E. Laurence, Joseph Leanza, Samuel Lewis, J. Austin Lee, Gideon Loevinsohn, Parker Maddox, Mallika Manyapu, Michael Mathelier, Kevin J. Mercer, Rmaah Memon, Kevin Molyneux, Dana Naamani, Benjamin D. Nicholson, Hannah Ofosua Owusu, Gerard M. O’Reilly, Mayur Patel, Nana Serwaa Agyeman Quao, Sarah Rapaport, Chris A. Rees, Charlotte Roy, Megan M. Rybarczyk, Jessica Schmidt, Megan L. Schultz, Anand Selvam, Erin F. Shufflebarger, Yusra Shakil, Branden Skarpiak, Cheyenne Smith, Jonathan M. Strong, Janet Jebichii Sugut, Fadhila Tekka, W. Tyler Winders, Ann Wolski, Natalie Yabalwashi   +85 more
wiley   +1 more source

Treatment of Febrile Neutropenia and Prophylaxis in Hematologic Malignancies: A Critical Review and Update

Advances in Hematology, 2014
Febrile neutropenia is one of the most serious complications in patients with haematological malignancies and chemotherapy. A prompt identification of infection and empirical antibiotic therapy can prolong survival.
Paola Villafuerte-Gutierrez, Lucia Villalon, Juan E. Losa, Cesar Henriquez-Camacho   +3 more
doaj   +1 more source

Efbemalenograstim alfa, an Fc fusion protein, long-acting granulocyte-colony stimulating factor for reducing the risk of febrile neutropenia following chemotherapy: results of a phase III trial [PDF]

, 2023
John A. Glaspy, Igor Bondarenko, Olga Burdaeva, Jianmin Chen, Dean Rutty, Renshu Li, Shufang Wang, Qingsong Hou, Simon Li   +8 more
openalex   +1 more source

Real‐World Survival Outcomes of Patients With High PD‐L1 Advanced NSCLC Who Received Chemoimmunotherapy Versus Immunotherapy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Are two drugs better than one in advanced NSCLC? ABSTRACT Background Randomized studies have demonstrated superior overall survival (OS) of pembrolizumab (pembro), both alone and in combination with chemotherapy (chemo) over chemo alone in patients with programmed cell death ligand‐1 (PD‐L1) ≥ 50% advanced non–small cell lung cancer (NSCLC).
Junipearl Cheng, Charlotte McKay, Victoria Bray, Po Yee Yip, Annette Tognela, Peey Sei Kok   +5 more
wiley   +1 more source