Educational Case: Febrile Nonhemolytic Transfusion Reaction [PDF]
The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology.
Aaron D. Shmookler MD +1 more
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Impact of buffy coat reduction on the severity of febrile nonhemolytic transfusion reactions with red cell components [PDF]
BACKGROUND: Febrile nonhemolytic transfusion reactions (FNHTRs) are the most common adverse reaction reported under the Haemovigilance Programme of India, and the use of leukodepleted blood products is recommended. The severity of the reaction may affect
Lakhvinder Singh +4 more
doaj +4 more sources
A Prospective Multicenter Observational Study Assessing Incidence and Risk Factors for Acute Transfusion Reactions in Cats [PDF]
Background The reported incidence of blood product transfusion reaction (TR) in cats varies greatly. Objective Evaluate the incidence and practices surrounding acute TRs in cats receiving feline blood products, using Transfusion Reaction Small Animal ...
Georgina B. F. Hall +18 more
doaj +2 more sources
Evaluation of leukocyte depletion of packed red blood cells for the prevention of clinically observed transfusion reactions at a medical center in Eastern Taiwan [PDF]
Objectives: The incidence of febrile nonhemolytic transfusion reactions (FNHTRs) is correlated with the level of cytokines released by donor leukocytes in blood bags during storage, which is the most common transfusion reaction. The study aimed to reveal
Kai-Yun Su +3 more
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Feeling the burn: the significant burden of febrile nonhemolytic transfusion reactions [PDF]
BACKGROUNDFebrile nonhemolytic transfusion reactions (FNHTRs) are characterized by a post‐transfusion temperature rise (of ≥ 1°C, to ≥ 38°C) or chills/rigors unrelated to the underlying condition. FNHTRs are provoked by inflammatory cytokines in the product or by host antileukocyte antibodies against residual donor leukocytes. FNHTRs are among the most
Robert Cohen +2 more
exaly +3 more sources
Effects of Prestorage vs Poststorage Leukoreduction on the Rate of Febrile Nonhemolytic Transfusion Reactions to Platelets [PDF]
The purpose of this study was to assess the incidence of febrile nonhemolytic transfusion reactions (FNHTRs) to concurrent transfusions of prestorage-leukoreduced (PreSLR) pooled platelets, poststorage-leukoreduced (PostSLR) pooled platelets, nonleukoreduced (NonLR) pooled platelets, and apheresis single-donor platelets (SDPs) to compare the rates of ...
Darrell J Triulzi +2 more
exaly +3 more sources
Acetaminophen and Diphenhydramine Premedication for Allergic and Febrile Nonhemolytic Transfusion Reactions: Good Prophylaxis or Bad Practice? [PDF]
Febrile nonhemolytic and allergic reactions are the most common transfusion reactions, but usually do not cause significant morbidity. In an attempt to prevent these reactions, US physicians prescribe acetaminophen or diphenhydramine premedication before more than 50% of blood component transfusions.
Terrence L Geiger, Scott C Howard
exaly +3 more sources
Randomized double‐blinded clinical trial on acute transfusion reactions in dogs receiving leukoreduced versus nonleukoreduced packed red blood cells [PDF]
Background Leukoreduction of blood products is commonly performed in human medicine, but its effect on outcome or incidence of transfusion reactions (TRs) in dogs is unknown.
Sinziana Maria Radulescu +4 more
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Febrile Nonhemolytic Transfusion Reactions
Abstract Context .—Febrile nonhemolytic transfusion reactions (FNHTRs) cause unwelcome interruptions during the course of blood product transfusions and necessitate measures to verify the nature of the reaction and to exclude certain dangerous reactions, such as hemolytic and septic phenomena.
Karen C Kelly, John Bernard Henry
exaly +3 more sources
Background: Blood transfusion reactions contribute significantly to the morbidity and mortality of both in- and outpatients in hospitals globally. Developing adequate protocols for detecting and reporting this complication is key to attaining global ...
John C Aneke +8 more
doaj +1 more source

