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Nonhemolytic Febrile Transfusion Reactions
Vox Sanguinis, 1966SummaryThe conditions under which nonhemolytic febrile transfusion reactions developed in eight afebrile patients were investigated. Recipients invariably developed a reaction on transfusion of incompatible white cells if a sufficient quantity of leukocytes was infused. The sensitivity of each patient differed with respect to the number of incompatible
H A Perkins, Rose Payne
exaly +4 more sources
BACKGROUND: Febrile nonhemolytic transfusion reactions occur in 0.12% of transfusions, usually during transfusion or within 4 to 6 hours after transfusion and are not medically dangerous.CASE REPORT: A patient with thalassemia from Togo with asymptomatic malaria in which the infection became clinically manifest only after blood transfusion, mimicking a
C. Boschetti +8 more
core +4 more sources
Febrile nonhemolytic transfusion reactions to platelets
Current Opinion in Hematology, 1995Although febrile nonhemolytic transfusion reactions to erythrocytes and platelets are not life threatening, the clinical symptoms associated with them cause discomfort for the patient, result in the use of premedicative drugs, and utilize nursing and laboratory resources.
Nancy M Heddle
exaly +3 more sources
Pathophysiology of febrile nonhemolytic transfusion reactions
Current Opinion in Hematology, 1999Most febrile nonhemolytic transfusion reactions (FNHTR) to platelets are caused by cytokines that accumulate in the product during storage. There have been numerous studies that have demonstrated high concentrations of leukocyte- and platelet-derived cytokines in stored platelet products.
Nancy M Heddle
exaly +3 more sources
Transfusion, 1962
In more than ten thousand transfusions given over a four‐year period to 1,649 patients, the incidence of urticarial reactions was 1.1 per cent. There were no hemolytic transfusion reactions and none due to bacterial contamination or to bacterial pyrogens.
Paul J Schmidt +2 more
exaly +3 more sources
In more than ten thousand transfusions given over a four‐year period to 1,649 patients, the incidence of urticarial reactions was 1.1 per cent. There were no hemolytic transfusion reactions and none due to bacterial contamination or to bacterial pyrogens.
Paul J Schmidt +2 more
exaly +3 more sources
Transfusion and Apheresis Science, 2008
Accumulated inflammatory cytokines are considered to be a cause of febrile nonhemolytic transfusion reactions (FNHTRs) of platelet transfusions. Inflammatory cytokines have been found in red cell components stored at 4 degrees C; however, their relationship to FNHTRs has not been clearly demonstrated following red cell transfusions.
Tetsunori, Tasaki +7 more
exaly +3 more sources
Accumulated inflammatory cytokines are considered to be a cause of febrile nonhemolytic transfusion reactions (FNHTRs) of platelet transfusions. Inflammatory cytokines have been found in red cell components stored at 4 degrees C; however, their relationship to FNHTRs has not been clearly demonstrated following red cell transfusions.
Tetsunori, Tasaki +7 more
exaly +3 more sources
Transfusion, 2004
BACKGROUND: Febrile nonhemolytic transfusion reactions (FNHTR) is a relatively common complication associated with allogeneic transfusion. Because WBCs have been implicated in the mechanism of FNHTRs, it has been proposed that the transfusion of leukoreduced RBCs should be associated with a decreased incidence of FNHTRs.
Karen E KING, R Sue Shirey, Paul M Ness
exaly +3 more sources
BACKGROUND: Febrile nonhemolytic transfusion reactions (FNHTR) is a relatively common complication associated with allogeneic transfusion. Because WBCs have been implicated in the mechanism of FNHTRs, it has been proposed that the transfusion of leukoreduced RBCs should be associated with a decreased incidence of FNHTRs.
Karen E KING, R Sue Shirey, Paul M Ness
exaly +3 more sources

