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Clinical significance of white cell antibodies in febrile nonhemolytic transfusion reactions
Transfusion, 1990Febrile nonhemolytic transfusion reactions (FNHTRs) are associated with white cell (WBC) antibodies. The purposes of this study were to determine the frequency of WBC antibodies, to associate the severity of reactions with antibody specificity, and to distinguish FNHTRs from infection and postoperative fever.
exaly +3 more sources
Febrile Nonhemolytic Transfusion Reactions
Clinical Journal of Oncology Nursing, 2002A. FNHTRs are reported in 0.5%–5% of all transfusions. B. FNHTRs are the most common complication of platelet transfusion. 1. Incidence ranges from 1.7% to 31%. 2. Higher incidences are seen in patients who have received multiple prior transfusions. C. Incidence may decrease with increased use of prestorage leukocytereduced blood products. D.
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Journal of Cardiothoracic and Vascular Anesthesia, 2000
IN 1994, APPROXIMATELY 500,000 patients in the United States underwent cardiac surgery employing cardiopulmonary bypass.1 Cardiopulmonary bypass is associated with deleterious effects on platelet number and function, leading to excessive bleeding in 5% to 25% of patients.2,3 About half of the 7 million units of platelets transfused annually in the ...
A D, Sharma, H P, Grocott
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IN 1994, APPROXIMATELY 500,000 patients in the United States underwent cardiac surgery employing cardiopulmonary bypass.1 Cardiopulmonary bypass is associated with deleterious effects on platelet number and function, leading to excessive bleeding in 5% to 25% of patients.2,3 About half of the 7 million units of platelets transfused annually in the ...
A D, Sharma, H P, Grocott
openaire +2 more sources
Transfusion, 2004
BACKGROUND: Febrile non‐hemolytic transfusion reactions (FNHTRs) are a common complication of platelet concentrate (PC) and RBC transfusions, usually ascribed to cytokines released by WBCs and perhaps the platelets themselves during storage. Prestorage WBC reduction should abrogate the accumulation of these cytokines reducing the number of FNHTRs ...
Mark H, Yazer +3 more
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BACKGROUND: Febrile non‐hemolytic transfusion reactions (FNHTRs) are a common complication of platelet concentrate (PC) and RBC transfusions, usually ascribed to cytokines released by WBCs and perhaps the platelets themselves during storage. Prestorage WBC reduction should abrogate the accumulation of these cytokines reducing the number of FNHTRs ...
Mark H, Yazer +3 more
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Transfusion, 2000
BACKGROUND: Febrile nonhemolytic transfusion reactions (FNHTRs) to platelet transfusions have been linked to the presence of cytokines in supernatant plasma. Cytokine concentration is directly related to WBC content and storage time. This study evaluated the effect of limiting the storage time of random‐donor platelet concentrates on the FNHTR rate ...
D L, Kelley +3 more
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BACKGROUND: Febrile nonhemolytic transfusion reactions (FNHTRs) to platelet transfusions have been linked to the presence of cytokines in supernatant plasma. Cytokine concentration is directly related to WBC content and storage time. This study evaluated the effect of limiting the storage time of random‐donor platelet concentrates on the FNHTR rate ...
D L, Kelley +3 more
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Journal of Pediatric Oncology Nursing, 2014
Transfusion-related reactions cause unwanted interruptions in blood-product administration and potential complications for patients. The most common reactions are febrile nonhemolytic transfusion reactions (FNHTRs) and allergic transfusion reactions (ATRs).
Joana, Duran +2 more
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Transfusion-related reactions cause unwanted interruptions in blood-product administration and potential complications for patients. The most common reactions are febrile nonhemolytic transfusion reactions (FNHTRs) and allergic transfusion reactions (ATRs).
Joana, Duran +2 more
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Zhongguo shi yan xue ye xue za zhi, 2003
The objective was designed to assess the clinical efficiency of preventing febrile nonhemolytic transfusion reactions (FNHTR) with transfusion of leukocyte-depleted RBC and platelet concentrates. One hundred patients with cirrhosis of liver, gastric ulcer and cancer were selected to receive RBC concentrates with leukocyte filtration.
Shu-Ming, Zhao +5 more
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The objective was designed to assess the clinical efficiency of preventing febrile nonhemolytic transfusion reactions (FNHTR) with transfusion of leukocyte-depleted RBC and platelet concentrates. One hundred patients with cirrhosis of liver, gastric ulcer and cancer were selected to receive RBC concentrates with leukocyte filtration.
Shu-Ming, Zhao +5 more
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International Blood Research & Reviews, 2014
Background: Febrile nonhemolytic transfusion reactions (FNHTRs) are common complications associated with allogenic transfusion and it is caused by the leucocytes and cytokines released by leucocytes during ...
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Background: Febrile nonhemolytic transfusion reactions (FNHTRs) are common complications associated with allogenic transfusion and it is caused by the leucocytes and cytokines released by leucocytes during ...
openaire +1 more source