Results 141 to 150 of about 120,188 (203)

Rare genetic variation in adults with surgically treated temporal lobe epilepsy: An exome sequencing study

Epilepsia Open, EarlyView.
Abstract Objective To determine the frequency of monogenic variants and pathogenic copy number variants (CNVs) in adults with surgically treated temporal lobe epilepsy (TLE). Methods We performed exome sequencing (ES), including CNV analysis, in 45 adults with TLE who had previously undergone epilepsy surgery.
Antonia P. Pirker, Margot Ernst, Matias Wagner, Silvia B. Bonelli, Karin Trimmel, Judith Jud, Elisabeth Graf, Christian Dorfer, Karl Rössler, Susanne Aull‐Watschinger, Ekaterina Pataraia, Fritz Zimprich, Martin Krenn   +12 more
wiley   +1 more source

Silence around SUDEP and its impact on caregivers of individuals with developmental and epileptic encephalopathies: An international survey

Epilepsia Open, EarlyView.
Abstract Objective Sudden Unexpected Death in Epilepsy (SUDEP) is the leading cause of epilepsy‐related mortality, particularly in individuals with Developmental and Epileptic Encephalopathies (DEEs). The goal of this work is to assess SUDEP‐related knowledge, information practices, emotional and psychological impact, and the use of preventive measures
José Ángel Aibar, Ana Cantó Martínez, David Alarcón Alarcón, Eulalia Turón‐Viñas, Rima Nabbout, Isabella Brambilla, Franck Kalume, Danielle Andrade, Simona Giorgi   +8 more
wiley   +1 more source

Lacrimal caruncula thermography overestimates rectal temperature in horses: Influence of camera type and measurement distance

Equine Veterinary Journal, EarlyView.
Abstract Background Rectal temperature (RT) is the gold standard for assessing body temperature in horses, but handling and welfare concerns limit its use. Thermography of the lacrimal caruncula (LC) has been proposed as a noncontact alternative, although its accuracy may be influenced by device characteristics and measurement distance.
Ömer Tarık Orhun, Ferda Turgut, Sıtkıcan Okur, Taner Arslan, Latif Emrah Yanmaz   +4 more
wiley   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Interview with Ruotong Chen, recipient of the 2026 Epilepsia Open Prize for Clinical Research

Epilepsia Open, EarlyView.
Merab Kokaia, Piero Perucca
wiley   +1 more source

Postpartum febrile morbidity following vacuum‐assisted birth: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate whether vacuum‐assisted birth (VAB) independently increases the risk of postpartum febrile morbidity, identifying a potentially modifiable contributor to maternal infectious morbidity. Methods This retrospective cohort study was conducted at a university‐affiliated tertiary maternity center between 2011 and 2023.
Itamar Gilboa, Daniel Gabbai, Lee Reicher, Emmanuel Attali, Yariv Yogev, Anat Lavie   +5 more
wiley   +1 more source

Improving healthcare value: Optimizing billing and documentation for inpatient addiction consultation services

Journal of Hospital Medicine, EarlyView.
Abstract Patients with substance use disorder (SUD) represent a high‐complexity, high‐cost population on hospital medicine services, yet their admissions are systematically under‐reimbursed due to narrow clinical documentation. Increasingly, hospital‐based addiction consultation service (ACS) clinicians provide dedicated addiction care to medically ...
Philip A. Durney, Nancy McLaughlin, Susan L. Calcaterra   +2 more
wiley   +1 more source

Variation in blood culture testing in children hospitalized with three common infections

Journal of Hospital Medicine, EarlyView.
Abstract Background Routine blood culture (BCx) testing in uncomplicated community‐acquired pneumonia (CAP), skin and soft tissue infections (SSTI), and urinary tract infections (UTI) has demonstrated low clinical utility. Objectives To evaluate hospital‐level BCx testing trends and their association with clinical outcomes for children hospitalized ...
Smit Shah, Jennifer L. Goldman, Matt Hall, John R. Stephens, Jillian M. Cotter, Samantha A. House, Matthew J. Molloy, Michelle Polich, Michael J. Steiner, Michael J. Tchou, Ronald J. Teufel II, Irma T. Ugalde, Andrew G. Yu, Jessica L. Markham   +13 more
wiley   +1 more source

Data‐Driven Insights into Hyperkinetic Disorders in Neurodevelopmental Syndromes and Epileptic Encephalopathies

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Childhood‐onset hyperkinetic movement disorders occur in a range of genetic conditions. Recently, there has been an increase in recognition of hyperkinetic movement disorders, mainly dystonia, chorea and dyskinesia, with monogenic conditions associated with neurodevelopmental delay (NDD) and also with developmental and epileptic ...
Hugo Morales‐Briceño, Shekeeb S. Mohammad, Rajeshwar Reddy Angiti, Velda Han, Michel Tchan, Russell C. Dale, Victor S.C. Fung   +6 more
wiley   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source