Results 51 to 60 of about 154,768 (166)

Advances in Fecal Microbiota Transplantation for Gut Dysbiosis‐Related Diseases

Advanced Science, Volume 12, Issue 13, April 3, 2025.
This article reviews the use of fecal microbiota transplantation (FMT) to treat intestinal diseases like recurrent Clostridioides difficile infection (rCDI), inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). It discusses FMT's efficacy, influencing factors such as donor selection, recipient characteristics, and treatment protocols ...
Shuna Hou, Jiachen Yu, Yongshuang Li, Duoyi Zhao, Zhiyu Zhang   +4 more
wiley   +1 more source

Metagenomic biomarker discovery and explanation [PDF]

, 2011
This study describes and validates a new method for metagenomic biomarker discovery by way of class comparison, tests of biological consistency and effect size estimation.
Garrett, Wendy S., Gevers, Dirk, Huttenhower, Curtis, Izard, Jacques, Miropolsky, Larisa, Segata, Nicola, Waldron, Levi   +6 more
core   +3 more sources

Effects of intratumoral microbiota on tumorigenesis, anti-tumor immunity, and microbe-based cancer therapy

Frontiers in Oncology
Intratumoral microbiota (IM) has emerged as a significant component of the previously thought sterile tumor microenvironment (TME), exerting diverse functions in tumorigenesis and immune modulation.
Jingwei Zheng, Hao Chen
doaj   +1 more source

Evolutionary biology and anthropology suggest biome reconstitution as a necessary approach toward dealing with immune disorders [PDF]

, 2013
Industrialized society currently faces a wide range of non-infectious, immune-related pandemics. These pandemics include a variety of autoimmune, inflammatory and allergic diseases that are often associated with common environmental triggers and with ...
Adler, Allen, Arbes, Backhed, Bagnasco, Bartlett, Becker, Becker, Bethell, Bickler, Bilbo, Bilbo, Black, Borkow, Brenner, Bronstein, Brown, Cannell, Capron, Casanova, Chandra, Correale, Correale, Dantzer, Davis, Day, de Borst, Devalapalli, Dominguez-Bello, Elliott, Fairweather, Fan, Fanaro, Fava, Feary, Feary, Feazel, Floch, Floch, Foliaki, Fumagalli, Gale, Gangoso, Gao, Genuis, Gernsbacher, Glaser, Gouin, Green, Grice, Guaraldi, Guarner, Guo, Hadley, Hanski, Hansson, Hare, Heck, Herre, Hewitson, Holick, Hummelen, Ippoliti, ISAAC Steering Committee, Isack, Jane Costello, Karst, Kelly, Kendall-Tackett, Khoruts, Kiecolt-Glaser, Kong, Krishnadas, Kronman, Lakhan, Leboyer, Lee, Lesher, Lin, Liu, Liu, Lowry, Lucas, Mackie, Malcolm, Mark, Mehta, Merrett, Meyer, Mills, Moylan, Nickens, Northrop-Clewes, Ollerton, Ollerton, Parker, Reiche, Rook, Rook, Rook, Rook, Rook, Ryder, Saha, Salim, Saunders, Sharief, Singh, Smith, Stojanovich, Strachan, Sullivan, Summers, Summers, Surawicz, Tilp, Trama, Turton, U.S. Food and Drug Administration, Valasquez-Manoff, van Nood, Vehik, von Hertzen, Waeber, Wang, Warren, Wilson, Wilson, Wohlleben, Wold, Yazdanbakhsh, Yoshioka, Zandman-Goddard, Zhou   +133 more
core   +1 more source

Cardiac Cachexia and the Associations to the Microbiome: State‐of‐the‐Science Review

JCSM Communications, Volume 8, Issue 1, January/June 2025.
ABSTRACT Background Cardiac cachexia is a late manifestation of advanced heart failure, with a 5%–15% prevalence. A diagnosis of cardiac cachexia is not simply another complication of heart failure; clinical consequences of cachexia are impaired physical function, fatigue, poor quality of life and independently associated with heart failure severity ...
Kelley M. Anderson, Amanda Schmitt, William S. Weintraub, Rebecca Scally, Tomoko Y. Steen   +4 more
wiley   +1 more source

Disruption of the gut microbiome as a risk factor for microbial infections [PDF]

, 2013
The discovery that microorganisms can be etiologic agents of disease has driven clinical, research and public health efforts to reduce exposure to bacteria.
Khosravi, Arya, Mazmanian, Sarkis K.
core   +1 more source

Regulatory T cells and their role in allergic disease

Allergy, Volume 80, Issue 1, Page 77-93, January 2025.
Abstract The incidence of allergic diseases has been rising over the past decades, and this troubling trend coincides with environmental changes such as shifts in diet and increased antibiotic use, both of which can impact our immune system. Allergic reactions occur when the immune system overreacts to normally harmless substances, and it is known that
Melanie L. Conrad, Gabriela Barrientos, Xuejun Cai, Saikat Mukherjee, Mrinmoy Das, Emmanuel Stephen‐Victor, Hani Harb   +6 more
wiley   +1 more source

A review of engraftment assessments following fecal microbiota transplant

Gut Microbes
Fecal Microbiota Transplant (FMT) is a treatment for recurrent Clostridium difficile infections and is being explored for other clinical applications, from alleviating digestive and neurological disorders, to restoring microbiomes impacted by cancer ...
Chloe Herman, Bridget M. Barker, Thais F. Bartelli, Vidhi Chandra, Rosa Krajmalnik-Brown, Mary Jewell, Le Li, Chen Liao, Florencia McAllister, Khemlal Nirmalkar, Joao B. Xavier, J. Gregory Caporaso   +11 more
doaj   +1 more source

Clearance of vancomycin- resistant Enterococcus concomitant with administration of a microbiota -based drug targeted at recurrent Clostridium difficile infection [PDF]

, 2016
Background. Vancomycin-resistant Enterococcus (VRE) is a major healthcare-associated pathogen and a well known complication among transplant and immunocompromised patients.
Dubberke, Erik R, Gerding, Dale N, Guthertz, Harriet, Jones, Courtney, Lee, Christine H, Louie, Thomas J, Mullane, Kathleen M   +6 more
core   +2 more sources

Fecal microbiota transplantation unveils sex-specific differences in a controlled cortical impact injury mouse model

Frontiers in Microbiology
IntroductionContusion type of traumatic brain injury (TBI) is a major cause of locomotor disability and mortality worldwide. While post-TBI deleterious consequences are influenced by gender and gut dysbiosis, the sex-specific importance of commensal gut ...
Tulasi Pasam, Manoj P. Dandekar
doaj   +1 more source