Radiation reduces A. muciniphila‐derived 3HB concentration in the gut and serum, thereby elevating the expression of proinflammatory IL6 via GPR43‐mediated pathway, resulting in the exacerbation of tissue damage. This study demonstrate that intervention of gut dysbiosis and abnormal metabolomic network by gavage of probiotic A.
Zhenhuang Ge +13 more
wiley +1 more source
Clostridium difficile infection : considerations for hospitalists [PDF]
As hospitalists, we often care for patients who either present with diarrhea or develop diarrhea during their hospital visit. We have learned to think of Clostridium difficile infection (CDI) early.
Hahn-Cover, Kristin
core +1 more source
The skin microbiome in pediatric atopic dermatitis and food allergy
Abstract The skin microbiome is an extensive community of bacteria, fungi, mites, viruses and archaea colonizing the skin. Fluctuations in the composition of the skin microbiome have been observed in atopic dermatitis (AD) and food allergy (FA), particularly in early life, established disease, and associated with therapeutics.
Elizabeth Huiwen Tham +5 more
wiley +1 more source
Antibiotics, gut microbiota, environment in early life and type 1 diabetes [PDF]
The gut microbiota interact with innate immune cells and play an important role in shaping the immune system. Many factors may influence the composition of the microbiota such as mode of birth, diet, infections and medication including antibiotics.
Hu, Youjia +2 more
core +2 more sources
Convergence of Nanotechnology and Bacteriotherapy for Biomedical Applications
Nanoparticles and bacteria integration holds promise for diverse biomedical applications. This review summarizes strategies and design principles to construct effective delivery/therapeutic platforms combining nanoparticles and bacteria, with a focus on emerging disease diagnosis and treatment applications. Furthermore, the microbiota modulation effect
Jun Liu +3 more
wiley +1 more source
Fecal Microbiota Transplant for Relapsing Clostridium difficile Infection Using a Frozen Inoculum From Unrelated Donors: A Randomized, Open-Label, Controlled Pilot Study [PDF]
Fecal microbiota transplant is increasingly used to treat recurrent or relapsing Clostridium difficile infection. In this randomized controlled study, using a frozen inoculum from unrelated donors was safe and effective, whether administered by ...
Alm, Eric J +9 more
core +1 more source
Nurturing longevity through natural compounds: Where do we stand, and where do we go?
Abstract The revolution in aging research through the past decade has driven the progress in interventions that promote longevity. Dissection of the “old” hallmarks of aging has provided solid data for the definition of at least three “new” ones, opening avenues for the development of novel hallmark‐targeted pro‐longevity approaches.
Monika N. Todorova +3 more
wiley +1 more source
The role of gut microbiota in cerebrovascular disease and related dementia
Abstract In recent years, increasing evidence suggests that commensal microbiota may play an important role not only in health but also in disease including cerebrovascular disease. Gut microbes impact physiology, at least in part, by metabolizing dietary factors and host‐derived substrates and then generating active compounds including toxins.
María Isabel Cuartero +7 more
wiley +1 more source
Effects of Clostridium difficile on the human immune response [PDF]
Clostridium difficile is a bacterium that is rapidly becoming a large issue in the medical community due to its tendency to infect hospital patients and its resistance to antibiotics.
McGovern, Mike
core +1 more source
Heterogeneity of the gut microbiome in mice : guidelines for optimizing experimental design [PDF]
Targeted manipulation of the gut flora is increasingly being recognized as a means to improve human health. Yet, the temporal dynamics and intra- and interindividual heterogeneity of the microbiome represent experimental limitations, especially in human ...
Brinkman, Brigitta +4 more
core +1 more source

