Nurturing longevity through natural compounds: Where do we stand, and where do we go?
Abstract The revolution in aging research through the past decade has driven the progress in interventions that promote longevity. Dissection of the “old” hallmarks of aging has provided solid data for the definition of at least three “new” ones, opening avenues for the development of novel hallmark‐targeted pro‐longevity approaches.
Monika N. Todorova +3 more
wiley +1 more source
Clostridium difficile infection : considerations for hospitalists [PDF]
As hospitalists, we often care for patients who either present with diarrhea or develop diarrhea during their hospital visit. We have learned to think of Clostridium difficile infection (CDI) early.
Hahn-Cover, Kristin
core +1 more source
The role of gut microbiota in cerebrovascular disease and related dementia
Abstract In recent years, increasing evidence suggests that commensal microbiota may play an important role not only in health but also in disease including cerebrovascular disease. Gut microbes impact physiology, at least in part, by metabolizing dietary factors and host‐derived substrates and then generating active compounds including toxins.
María Isabel Cuartero +7 more
wiley +1 more source
Heterogeneity of the gut microbiome in mice : guidelines for optimizing experimental design [PDF]
Targeted manipulation of the gut flora is increasingly being recognized as a means to improve human health. Yet, the temporal dynamics and intra- and interindividual heterogeneity of the microbiome represent experimental limitations, especially in human ...
Brinkman, Brigitta +4 more
core +1 more source
Genetically Engineered Microorganisms and Their Impact on Human Health
The emergence of antibiotic‐resistant strains, the decreased effectiveness of conventional therapies, and the side effects have led researchers to seek a safer, more cost‐effective, patient‐friendly, and effective method that does not develop antibiotic resistance.
Marzie Mahdizade Ari +5 more
wiley +1 more source
Effects of Clostridium difficile on the human immune response [PDF]
Clostridium difficile is a bacterium that is rapidly becoming a large issue in the medical community due to its tendency to infect hospital patients and its resistance to antibiotics.
McGovern, Mike
core +1 more source
Clostridium difficile infection. [PDF]
Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life threatening, especially in elderly people and in patients who have dysbiosis of the gut microbiota following antimicrobial drug exposure. C.
A Antunes +255 more
core +1 more source
European consensus conference on faecal microbiota transplantation in clinical practice [PDF]
Faecal microbiota transplantation (FMT) is an important therapeutic option for Clostridium difficile infection. Promising findings suggest that FMT may play a role also in the management of other disorders associated with the alteration of gut microbiota.
Aloi, Marina +28 more
core +2 more sources
Clostridium difficile infection (CDI) is the leading cause of antibiotic-associated diarrhea and has gained worldwide notoriety due to emerging hypervirulent strains and the high incidence of recurrence. We previously reported protection of mice from CDI
Abel-Santos, Ernesto +9 more
core +1 more source
Fecal Microbiota Transplant for Relapsing Clostridium difficile Infection Using a Frozen Inoculum From Unrelated Donors: A Randomized, Open-Label, Controlled Pilot Study [PDF]
Fecal microbiota transplant is increasingly used to treat recurrent or relapsing Clostridium difficile infection. In this randomized controlled study, using a frozen inoculum from unrelated donors was safe and effective, whether administered by ...
Alm, Eric J +9 more
core +1 more source

