Results 61 to 70 of about 6,646 (285)

Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery

open access: yesAdvanced Robotics Research, EarlyView.
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang   +9 more
wiley   +1 more source

Milk Alkali Syndrome Complicated by Calcium Impaction Causing Bowel Perforation

open access: yesAnnals of Internal Medicine: Clinical Cases, 2022
The milk-alkali syndrome consists of hypercalcemia, metabolic alkalosis, and acute kidney injury associated with the ingestion of large amounts of calcium and absorbable alkali. There has been a resurgence of this condition because of calcium therapy for
Sharonya Shrivastava   +2 more
doaj   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

open access: yesAdvanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis   +7 more
wiley   +1 more source

Fecaloma presenting as huge abdominal mass

open access: yesJGH Open, 2020
Fecal impaction is common in elderly, bed ridden, schizoaffective patients on antipsychotics. Intestinal obstruction due to distal colonic fecaliths is rare as it is amenable to digital manual evacuation and enemas.
Mushtaq A Khan   +6 more
doaj   +1 more source

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue‐Resident Memory T Cells via Altering Skin Microbiota

open access: yesAdvanced Science, EarlyView.
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang   +10 more
wiley   +1 more source

A case report of impacted fecalith within mucosal pouch: an unusual cause of colocolic intussusception [PDF]

open access: yesAnnals of Coloproctology
Intussusception involving the colon is unusual in adults and when present is managed with resection due to the risk of malignancy. We present an unusual case where the intussusceptum was impacted stool in a mucosal pouch in the transverse colon.
Douglas Greer, Adrian Fernandez
doaj   +1 more source

Savory satisfaction can lead to lower gastrointestinal impaction [PDF]

open access: yes, 2013
The differential diagnosis for constipation is large and includes many common diagnoses as well asother unusual ones. Bezoars are one of the diagnostic "zebras" that we do not think of frequently.Bezoars are foreign material masses that are formed in the
Hammad, Hazem   +2 more
core  

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

open access: yesAdvanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol   +18 more
wiley   +1 more source

Time Course of Treatment for Primary Enuresis With Overactive Bladder [PDF]

open access: yesInternational Neurourology Journal, 2018
Purpose To characterize the course of treatment for nonmonosymptomatic enuresis with overactive bladder (OAB) in a real clinical setting. Methods Data from 111 OAB patients with moderate to severe enuresis were analyzed.
Young Jae Im   +2 more
doaj   +1 more source

What treatments work best for constipation in children? [PDF]

open access: yes, 2009
Osmotic laxatives produce the best results. Fiber and behavior modification may have a role. Increased fiber and behavior modification are the most often recommended first steps in managing chronic functional constipation (CFC) in children, but only ...
Carter, Nakia Joyce   +2 more
core  

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