Protection of hamsters from mortality by reducing fecal moxifloxacin concentration with DAV131A in a model of moxifloxacin-induced Clostridium difficile colitis [PDF]
BackgroundLowering the gut exposure to antibiotics during treatments can prevent microbiota disruption. We evaluated the effect of an activated charcoal-based adsorbent, DAV131A, on fecal free moxifloxacin concentration and mortality in a hamster model of moxifloxacin-induced C.
arxiv +1 more source
Double-blind randomised controlled trial of percutaneous tibial nerve stimulation versus sham electrical stimulation in the treatment of faecal incontinence: CONtrol of Faecal Incontinence using Distal NeuromodulaTion (the CONFIDeNT trial) [PDF]
Background: Faecal incontinence (FI) is a common condition which is often under-reported. It is distressing for those suffering from it, impacting heavily on their quality of life.
Allescher+81 more
core +2 more sources
SARS-CoV-2's closest relative, RaTG13, was generated from a bat transcriptome not a fecal swab: implications for the origin of COVID-19 [PDF]
RaTG13 is the closest related coronavirus genome phylogenetically to SARS-CoV-2, consequently understanding its provenance is of key importance to understanding the origin of the COVID-19 pandemic. The RaTG13 NGS dataset is attributed to a fecal swab from the intermediate horseshoe bat Rhinolophus affinis.
arxiv
Fecal incontinence - Challenges and solutions.
Fecal incontinence is not a diagnosis but a frequent and debilitating common final pathway symptom resulting from numerous different causes. Incontinence not only impacts the patient's self-esteem and quality of life but may result in significant ...
Nallely Saldana Ruiz, A. Kaiser
semanticscholar +1 more source
Incontinence and quality of life in ulcerative colitis patients after total proctocolectomy with an ileal pouch anal anastomosis [PDF]
Objective: Total proctocolectomy with ileal pouch-anal anastomosis (IPAA) is a surgical procedure performed on patients with ulcerative colitis (UC) to avoid the need for permanent stoma.
Seyed Vahid Hosseini+6 more
doaj +1 more source
Examining professionals' and parents' views of using transanal irrigation with children: Understanding their experiences to develop a shared health resource for education and practise [PDF]
Irrigation as a bowel management approach has been reportedly used with children for more than 20 years. Parents managing their child's chronic bowel problem have previously been shown to have increased emotional stress.
Bray, L., Sanders, C
core +1 more source
Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a. [PDF]
A comprehensive genomic and proteomic, computational, and physiological approach was employed to examine the (previously unexplored) role of microRNAs (miRNAs) as regulators of internal anal sphincter (IAS) smooth muscle contractile phenotype and basal ...
Addya, Sankar+6 more
core +3 more sources
In Japan, the surgical treatment for fecal incontinence (FI) can be performed using minimally invasive surgery, such as anal sphincteroplasty and sacral neuromodulation (SNM), as well as antegrade continence enema (ACE), graciloplasty, and stoma ...
Kotaro Maeda+8 more
doaj +1 more source
BackgroundAnal sphincter defects are a major cause of fecal incontinence causing negative effects on daily life, social interactions, and mental health.
A. Sarveazad+6 more
semanticscholar +1 more source
Effects of abdominal and vaginal hysterectomy on anorectal functions along with quality of life of the patient [PDF]
Objectives and background:Hysterectomy is the most commonly performed major gynecological operation for both benign and malign gynecologic conditions.
Birsen, Onur+3 more
core +3 more sources