Results 51 to 60 of about 244,874 (266)

Catheter Injectable Multifunctional Biomaterial for the Treatment of Infected Enterocutaneous Fistulas

Advanced Science, EarlyView.
A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim, Zefu Zhang, Hassan Albadawi, Hyeongseop Keum, Joseph L. Mayer, Erin H. Graf, Rahmi Oklu   +6 more
wiley   +1 more source

The pathogenesis of cryptoglandular anal fistula: New insight into the immunological profile

Colorectal Disease, Volume 24, Issue 12, Page 1567-1575, December 2022., 2022
Abstract Aim The aetiology of cryptoglandular anal fistula (AF) is poorly understood. Evidence suggests that persistence and/or recurrence of the disease is more related to inflammatory than infectious factors. The aim of this study was to investigate the immune profile of cryptoglandular AF and to perform a histopathological characterization.
Francesco Litta, Andrea Papait, Donatella Lucchetti, Serafina Farigu, Angelo Parello, Claudio Ricciardi Tenore, Paola Campennì, Antonietta Rosa Silini, Maria Cristina Giustiniani, Ornella Parolini, Alessandro Sgambato, Carlo Ratto   +11 more
wiley   +1 more source

On the prevalence of constipation and fecal incontinence, and their co-occurrence, in the Netherlands

International Journal of Colorectal Disease, 2016
PurposeNumerous studies have investigated the prevalence of constipation and fecal incontinence (FI) in the general population and, even though these disorders are known to co-occur, they were studied independently of each other.
Rob J Meinds, M. M. van Meegdenburg, M. Trzpis, P. Broens   +3 more
semanticscholar   +1 more source

Subcutaneous incision of the fistula tract and internal sphincterotomy (SIFT‐IS): a novel surgical procedure for transsphincteric anal fistula

Colorectal Disease, Volume 24, Issue 12, Page 1576-1583, December 2022., 2022
Abstract Aim The aetiology of anal fistula has not been fully clarified. One of the causes of anal fistulas may be the markedly deep crypts that characterize the primary openings. We developed subcutaneous incision of the fistula tract and internal sphincterotomy (SIFT‐IS) to eradicate these deep crypts.
Rikisaburo Sahara, Michihiro Koizumi, Koji Morimoto, Itaru Kubota   +3 more
wiley   +1 more source

Detection of the most influential variables for preventing postpartum urinary incontinence using machine learning techniques [PDF]

Digital Health, Volume 8, 2022, 20552076221111289
Background: Postpartum urinary incontinence (PUI) is a common issue among postnatal women. Previous studies identified potential related variables, but lacked analysis on certain intrinsic and extrinsic patient variables during pregnancy. Objective: The study aims to evaluate the most influential variables in PUI using machine learning, focusing on ...
arxiv   +1 more source

Late anastomotic complication after laparoscopic surgery for clinical stage I low rectal cancers located within 5 cm of the anal verge: Sub‐analysis of the ultimate trial

Annals of Gastroenterological Surgery, EarlyView.
Anastomotic stenosis and late fistula formation frequently emerge as secondary consequences of early AL, and represent significant complications linked to permanent stoma creation, often proving resistant to treatment. Intestinal prolapse is a characteristic anastomotic complication of ISR that can be caused by excessive intestinal mobilization.
Manabu Shimomura, Masanori Yoshimitsu, Yuichiro Tsukada, Hideki Ohdan, Jun Watanabe, Yosuke Fukunaga, Yasumitsu Hirano, Kazuhiro Sakamoto, Hiroki Hamamoto, Hisanaga Horie, Nobuhisa Matsuhashi, Yoshiaki Kuriu, Shuntaro Nagai, Madoka Hamada, Shinichi Yoshioka, Shinobu Ohnuma, Tamuro Hayama, Koki Otsuka, Yusuke Inoue, Kazuki Ueda, Yuji Toiyama, Satoshi Maruyama, Shigeki Yamaguchi, Keitaro Tanaka, Motoko Suzuki, Toshihiro Misumi, Takeshi Naitoh, Masahiko Watanabe, Masaaki Ito, Ultimate Trial Group   +29 more
wiley   +1 more source

A Clinical and Finite Elements Study of Stress Urinary Incontinence in Women Using Fluid-Structure Interactions [PDF]

, 2017
Stress Urinary Incontinence (SUI) or urine leakage from urethra occurs due to an increase in abdominal pressure resulting from stress like a cough or jumping height. SUI is more frequent among post-menopausal women. In the absence of bladder contraction, vesical pressure exceeds from urethral pressure leading to urine leakage. Despite a large number of
arxiv   +1 more source

Autologous Myoblasts for the Treatment of Fecal Incontinence

Annals of Surgery, 2017
Objective: The aim of this study was to evaluate the efficacy of intrasphincteric injections of autologous myoblasts (AMs) in fecal incontinence (FI) in a controlled study.
O. Boyer, V. Bridoux, C. Giverne, A. Bisson, E. Koning, A. Leroi, P. Chambon, Justine Déhayes, S. Le corre, S. Jacquot, D. Bastit, J. Martinet, E. Houivet, J. Tuech, J. Benichou, F. Michot   +15 more
semanticscholar   +1 more source

Reoperative pouch surgery for suspected Crohn's‐related complications aided by biologic coverage: Early experience from an inflammatory bowel disease center

Annals of Gastroenterological Surgery, EarlyView.
This paper demonstrates that revisional/redo ileal pouch anal anastomosis (IPAA) surgery with concurrent biologic therapy provides a viable, stoma‐free alternative for patients with Crohn's disease‐like complications, showing a high functioning pouch rate and expanding options for managing pouch failure.
Mehmet Gulmez, Daniel J. Wong, Ariela K. Holmer, Eren Esen, Shannon Chang, Arman Erkan, David Hudesman, Andre da Luz Moreira, Feza H. Remzi   +8 more
wiley   +1 more source

Pharmacokinetic analysis on compatibility of Atractylodes macrocephala and Paeoniae radix herb pair ameliorates functional constipation model rats using microdialysis with ultra‐performance liquid chromatography

Animal Models and Experimental Medicine, EarlyView.
The active ingredient of the drug determines the effect of the drug, and the compatibility affects the content of the active ingredient of the drug, which in turn affects the exertion of the efficacy. This study partly clarifies the rationality and compatibility of AM‐PR in the treatment of FC.
Xiaoting Wang, Xiaojun Li, Rui Zhang, Yin Hong, Jiaqi Guan   +4 more
wiley   +1 more source