Results 91 to 100 of about 749,609 (349)

The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing [PDF]

, 2014
Peer ...
Parkhill Julian, Duncan Sylvia H., John M. Thomson (229314), Thomson, John M., Farquarson Freda M., Berry Susan H., Hold Georgina L., Hold, Georgina L., Harry J. Flint (125298), Flint, Harry James, Nicholas A. Kennedy (526553), Satsangi, Jack J., Kennedy, Nicholas A, Julian Parkhill (30393), Georgina L Hold, Farquarson, Freda M., Georgina L. Hold (229333), Lees Charlie W., Satsangi, Jack, UK IBD Genetics Consortium, Sylvia H. Duncan (125296), Jack Satsangi, Satsangi Jack, ?, ?, Hold, Georgina L, Lees, Charlie W., Nicholas A Kennedy, Sylvia H Duncan, Walker Alan W., Harry J Flint, Freda M. Farquarson (526554), Walker, Alan W, John M Thomson, Charlie W. Lees (526556), Flint Harry J., Kennedy, Nicholas A., Susan H. Berry (229319), Alan W. Walker (50247), Lees, Charlie W, Thomson John M., Flint, Harry J., Charlie W Lees, Petra Louis (526555), Walker, Alan W., Louis Petra, Mowat, Craig; id_orcid, Duncan, Sylvia H, Newman, William; id_orcid, Berry, Susan H, Farquarson, Freda M, Petra Louis, Julian Parkhill, Berry, Susan H., Alan W Walker, Jack Satsangi (259264), Louis, Petra, Susan H Berry, Duncan, Sylvia H., Parkhill, Julian, Freda M Farquarson, Thomson, John M, Kennedy Nicholas A.   +61 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Spatial host-microbiome profiling demonstrates bacterial-associated host transcriptional alterations in pediatric ileal Crohn’s disease

Microbiome
Background Crohn’s disease (CD) is a chronic inflammatory bowel disease involving complex relationships between the gut microbiome and host immune system.
Sooyoung Jang, Eun Joo Lee, Sowon Park, Hyeji Lim, Byungsoo Ahn, Yoon Huh, Hong Koh, Yu Rang Park   +7 more
doaj   +1 more source

The fecal microbiota of healthy donor horses and geriatric recipients undergoing fecal microbial transplantation for the treatment of diarrhea.

PLoS ONE, 2020
Background and aimsFecal microbial transplantation (FMT), a treatment for certain gastrointestinal conditions associated with dysbiosis in people, is also empirically employed in horses with colitis.
Caroline A McKinney, Bruno C M Oliveira, Daniela Bedenice, Mary-Rose Paradis, Melissa Mazan, Sophie Sage, Alfredo Sanchez, Giovanni Widmer   +7 more
doaj   +1 more source

Validation of a batch cultivation protocol for fecal microbiota of Kenyan infants

BMC Microbiology, 2023
Background The combination of cultivation studies with molecular analysis approaches allows characterization of the complex human gut microbiota in depth. In vitro cultivation studies of infants living in rural sub-Saharan Africa are scarce.
Carole Rachmühl, Christophe Lacroix, Ambra Giorgetti, Nicole U. Stoffel, Michael B. Zimmermann, Gary M. Brittenham, Annelies Geirnaert   +6 more
doaj   +1 more source

Fecal Microbiota and Gut Microbe-Derived Extracellular Vesicles in Colorectal Cancer

Frontiers in Oncology, 2021
The human microbiota comprises trillions of microbes, and the relationship between cancer and microbiota is very complex. The impact of fecal microbiota alterations on colorectal cancer (CRC) pathogenesis is emerging.
Jihye Park, Nam-Eun Kim, H. Yoon, C. Shin, Nayoung Kim, Dong-Ho Lee, Jae Yong Park, C. Choi, J. G. Kim, Yoon-Keun Kim, Tae-Seop Shin, Jinho Yang, Y. S. Park   +12 more
semanticscholar   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Comparative analysis of pyrosequencing and a phylogenetic microarray for exploring microbial community structures in the human distal intestine [PDF]

, 2009
BACKGROUND: Variations in the composition of the human intestinal microbiota are linked to diverse health conditions. High-throughput molecular technologies have recently elucidated microbial community structure at much higher resolution than was ...
Vos, W.M., de, Willem M de Vos, O\u27Toole, Paul W., Smidt, H., O'Sullivan, O., Janne Nikkilä, Claesson Marcus J., de Vos Willem M., Hauke Smidt, O'Sullivan, Orla, Marchesi, Julian Roberto, O\u27Sullivan, Orla, Ross R. Paul, Smidt, Hauka, Ross, R. Paul, Ross, R. P., Paul W O'Toole, Wang, Qiong, Orla O'Sullivan, O'Sullivan Orla, de Vos, W.M., Qiong Wang, Nikkilä Janne, O'Toole, Paul W., Claesson, M.J., Marchesi, J.R., O'Toole, P.W., Claesson, Marcus J., O'Toole, P. W., Wang, Q., de Vos, Willem M., Claesson, M. J., Julian R Marchesi, O'Toole Paul W., Marchesi, Julian R., Smidt, Hauke, Ross, R.P., Smidt Hauke, Nikkila, Janne, R Paul Ross, Marchesi Julian R., Ross, R Paul, Wang Qiong, De Vos, W. M., Nikkilä, J., Marcus J Claesson, O'Sullivan, Orla, O'Toole, Paul W.   +47 more
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Fecal microbiota of the synanthropic golden jackal (Canis aureus)

Animal Microbiome, 2023
The golden jackal (Canis aureus), is a medium canid carnivore widespread throughout the Mediterranean region and expanding into Europe. This species thrives near human settlements and is implicated in zoonoses such as rabies.
Roi Lapid, Yair Motro, Hillary Craddock, Boris Khalfin, Roni King, Gila Kahila Bar-Gal, Jacob Moran-Gilad   +6 more
doaj   +1 more source