Results 101 to 110 of about 80,269 (322)

Procedure, Screening, and Cost of Fecal Microbiota Transplantation [PDF]

, 2023
Austin Wynn, Garet Beyer, Megan Richards, Lisa Ennis   +3 more
openalex   +1 more source

The interplay of gut microbiota between donors and recipients determines the efficacy of fecal microbiota transplantation

Gut microbes, 2022
Fecal microbiota transplantation (FMT) is a promising treatment for microbiota dysbiosis associated diseases, such as Clostridioides difficile infection (CDI) and inflammatory bowel disease (IBD).
Ruiqiao He, Pan Li, Jinfeng Wang, Bota Cui, Faming Zhang, Fangqing Zhao   +5 more
semanticscholar   +1 more source

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source

Effects of semaglutide on metabolism and gut microbiota in high-fat diet-induced obese mice

Frontiers in Pharmacology
BackgroundThe purpose of this study was to explore how semaglutide, a GLP-1RA, regulates serum metabolism and gut microbiota to improve obesity in mice and whether fecal microbiota transplantation (FMT) can transmit the beneficial effects of semaglutide ...
Luyan Sun, Bingqing Shang, Suyuan Lv, Guolong Liu, Qiu Wu, Yue Geng   +5 more
doaj   +1 more source

Characterizing the gut microbiome in trauma: significant changes in microbial diversity occur early after severe injury. [PDF]

, 2017
Background:Recent studies have demonstrated the vital influence of commensal microbial communities on human health. The central role of the gut in the response to injury is well described; however, no prior studies have used culture-independent profiling
Calfee, Carolyn S, Callcut, Rachael A, Campion, Eric M, Christie, Sabrinah A, Cohen, Mitchell Jay, Conroy, Amanda S, Fadrosh, Douglas W, Howard, Benjamin M, Kornblith, Lucy Z, Lamere, Brandon J, Lynch, Susan, Nelson, Mary F   +11 more
core   +1 more source

Fecal Microbiota Transplantation Relieves Gastrointestinal and Autism Symptoms by Improving the Gut Microbiota in an Open-Label Study

Frontiers in Cellular and Infection Microbiology, 2021
Autism spectrum disorder (ASD) is a severe brain development disorder that is characterized by deficits in social communication and restricted, repetitive and stereotyped behaviors.
Ning Li, Hongyan Chen, Yi Cheng, Fenghua Xu, Guangcong Ruan, Senhong Ying, Wen Tang, Lu Chen, Minjian Chen, Linling Lv, Yi Ping, Dongfeng Chen, Yanling Wei   +12 more
semanticscholar   +1 more source

Gut–Metabolome–Proteome Interactions in Age‐Related Hearing Loss: Insights from Fecal Microbiota Transplantation and Multi‐Omics Analyses

Advanced Science, EarlyView.
Germ‐free (GF) mice receiving fecal microbiota transplantation (FMT) reveal microbiota‐dependent effects on auditory aging. Integrated metagenomic, metabolomic and proteomic profiling maps gut–inner ear network and highlights 5‐hydroxytryptophan (5‐HTP) as a microbiota‐linked metabolic hub in age‐related hearing loss (ARHL).
Ting Yang, Ziwen Gao, Hui Huang, Chanyuan Zhang, Yiquan Tang, Qianhui Qu, Huabin Li, Jing Ke, Zhiji Chen, Menglong Feng, Hu Zhou, Yilai Shu, Wei Yuan   +12 more
wiley   +1 more source

The early life microbiota protects neonatal mice from pathological small intestinal epithelial cell shedding [PDF]

, 2020
The early life gut microbiota plays a crucial role in regulating and maintaining the intestinal barrier, with disturbances in these communities linked to dysregulated renewal and replenishment of intestinal epithelial cells.
Alastair J. M. Watson, Cristina Alcon‐Giner, d'Hennezel E, Federico Bernuzzi, Gwénaëlle Le Gall, Hedblom GA, Kevin R. Hughes, Lindsay J. Hall, Lisa Chalklen, Matthew J. Dalby, Potten CS, Selma‐Royo M, Shabhonam Caim, Weiser MM, Zoe Schofield   +14 more
core   +1 more source

Metagenomic and metabolomic analyses reveal synergistic effects of fecal microbiota transplantation and anti-PD-1 therapy on treating colorectal cancer

bioRxiv, 2022
Anti-PD-1 immunotherapy has saved numerous lives of cancer patients; however, it only exerts efficacy in 10-15% of patients with colorectal cancer. Fecal microbiota transplantation (FMT) is a potential approach to improving the efficacy of anti-PD-1 ...
Jiayuan Huang, Xing Zheng, Wanying Kang, Huaijie Hao, Yu-Bin Mao, Hua Zhang, Yuan Chen, Yan Tan, Yu-long He, Wenjing Zhao, Yiming Yin   +10 more
semanticscholar   +1 more source

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source