Results 231 to 240 of about 29,988 (285)

Parkinson's Disease and Cancer: Mechanistic Insights and Therapeutic Opportunities From Cancer Neuroscience

open access: yesMedComm – Oncology, Volume 4, Issue 4, December 2025.
Parkinson's disease (PD) and glioma are neurological disorders with distinct and even opposing mechanisms: α‐synuclein deposition and neuronal loss in PD versus glial cell malignancy in glioma. Despite these differences, their contrasting pathologies highlight multiple therapeutic targets.
Tianli Pan   +7 more
wiley   +1 more source

Urinary metabolomic profiling in 22q11.2 deletion syndrome reveals microbial and mitochondrial signatures related to autism and psychosis risk

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 4, Issue 4, December 2025.
Abstract Aim 22q11.2 deletion syndrome (22qDS) is the most common copy‐number‐variation disorder, associated with multi‐organ anomalies and elevated risk for schizophrenia and other neuropsychiatric conditions. Previous metabolomic studies have used blood samples, implicating mitochondrial dysfunction and amino acid imbalance, but no urinary ...
Takuto Minami   +13 more
wiley   +1 more source

Akkermansia muciniphila Alleviates Olanzapine‐Induced Hepatic Steatosis via the Gut Microbiota‐IGFBP2/APOA1‐Liver Axis

open access: yesMicrobial Biotechnology, Volume 18, Issue 12, December 2025.
Olanzapine induces hepatic steatosis with differential susceptibility observed in both rats and patients, while A. muciniphila alleviates liver lipid accumulation and injury by modulating gut microbiota and hepatic gene expression. Overexpression of IGFBP2 and APOA1 further protects against olanzapine‐induced hepatic steatosis.
Jing Wang   +7 more
wiley   +1 more source

Therapeutic Potential of Fecal Microbiota Transplantation in Type 2 Diabetes Mellitus: A Systematic Review

open access: diamond
Muhammad Rizwan Aslam   +5 more
openalex   +1 more source

Targeted Therapy for Gut Microbiota: Candidates for a Novel Strategy to Ameliorate Type 2 Diabetes Mellitus

open access: yesMicrobial Biotechnology, Volume 18, Issue 12, December 2025.
Type 2 diabetes mellitus (T2DM) poses a significant threat to public health and is linked to the gut microbiota. Probiotics, prebiotics, and synbiotics, together with fecal microbiota transplantation (FMT), can restore the gut microbiota in type 2 diabetes mellitus (T2DM) patients.
Jiangyan Wang   +10 more
wiley   +1 more source

Propionic acid mediates the renoprotective effects of fecal microbiota transplantation against ischemia-reperfusion injury via upregulating GPR43. [PDF]

open access: yesFront Cell Infect Microbiol
Yu J   +15 more
europepmc   +1 more source

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