Results 241 to 250 of about 29,988 (285)

Inflammation in Diabetic Kidney Disease Is Linked to Gut Dysbiosis and Metabolite Imbalance

Journal of Diabetes, Volume 17, Issue 12, December 2025.
Gut barrier dysfunction and gut microbiota imbalance may mediate the pro‐inflammatory immune phenotype observed in patients with DKD and thereby contribute to DKD progression. These findings underscore the important role of the microbiota–immune axis in the development of DKD.
Xueting Zheng, Xiaoyan Luo, Yi Zhang, Zhiyan Zou, Jiayi Yang, Huan Liu, Zhou Lu, Fangfang Cao, Xilian Wang, Xinyun Ge, Xiaoan Li, Jiali Wang   +11 more
wiley   +1 more source

Fecal microbiota transplantation alleviated heat-induced colonic tissue damage, epithelial apoptosis, and oxidative stress. [PDF]

Appl Environ Microbiol
Liu X, Liu C, Qian X, Zhang S, Yao Z, Chai Y, Shi Q, Yang W, Wang Q, Zhang L, Zeng X, Liu C, Wu Y, Sun Q.   +13 more
europepmc   +1 more source

Impact of Fecal Microbiota Transplant Formulations, Storage Conditions, and Duration on Bacterial Viability, Functionality, and Clinical Outcomes in Patients with Recurrent <em>Clostridioides difficile </em>Infection

Mohamed Shaheen, Chelsea McDougall, Leona Chan, Rose Franz, Karen Wong, Ryland T. Giebelhaus, Gwen Nguyen, Seo Lin Nam, A. Paulina de la Mata, Sam Yeo, James J. Harynuk, Sepideh Pakpour, Huiping Xu, Dina Kao   +13 more
openalex   +1 more source

Defining Microbiota‐Derived Metabolite Butyrate as a Senomorphic: Therapeutic Potential in the Age‐Related T Cell Senescence

Aging Cell, Volume 24, Issue 12, December 2025.
An age‐associated accumulation of senescent T cells is characterized by increased cellular damage and the secretion of pro‐inflammatory molecules collectively known as the senescence‐associated secretory phenotype (SASP). In the present study, we demonstrate that this accumulation of senescent T cells in aged hosts is accompanied by a reduction in ...
Nia Paddison Rees, Jessica Conway, Ben Dugan, Sayeda S. Amir, Aimee Parker, Simon R. Carding, Niharika A. Duggal   +6 more
wiley   +1 more source

Exploring the role of gut microbiota in Parkinson's disease: insights from fecal microbiota transplantation. [PDF]

Front Neurosci
Guo M, Gao H, Wang Y, Xiang Y.
europepmc   +1 more source

Fecal Microbiota Transplantation of Patients with Anorexia Nervosa in an Activity-Based Anorexia Animal Model

Mai Tran, Clara Voelz, Larissa Käver, N. M. Korten, Ashley M. Eckel, Cordian Beyer, Jochen Seitz, Stefanie Trinh   +7 more
openalex   +1 more source

Baricitinib Augments Lonafarnib Therapy to Preserve Colonic Homeostasis and Microbial Balance in a Mouse Model of Progeria

Aging Cell, Volume 24, Issue 12, December 2025.
Combined baricitinib and lonafarnib treatment improved colonic pathology in LmnaG609G/G609G progeria mice by reducing progerin, maintaining epithelial regeneration, mitigating inflammation and senescence, and preserving microbiome composition. ABSTRACT Hutchinson‐Gilford Progeria Syndrome (HGPS) is a fatal genetic disorder caused by progerin, a mutant ...
Moritz Schroll, Yacine Amar, Peter Krüger, Klaus Neuhaus, Karima Djabali   +4 more
wiley   +1 more source

The efficacy and safety of fecal microbiota transplantation in the treatment of sarcopenia: a retrospective study. [PDF]

J Transl Med
Yang B, Li X, Wang J, Xu Y, Wang L, Wu Z, Zhao D, Huang L, Li N, Chen Q, Liu Z.   +10 more
europepmc   +1 more source

Study on the efficacy and mechanism of fecal microbiota transplantation for depression based on circadian rhythm

Yuhao Li, Shuo Zhang, Chuying Li, Ying Sun, Bei An   +4 more
openalex   +1 more source

Diversity and Dosage Determine the Efficacy of the Probiotic SYN‐53 in Allergic Rhinoconjunctivitis: A Randomized, Double‐Blind, Placebo‐Controlled Trial

Allergy, Volume 80, Issue 12, Page 3310-3318, December 2025.
The probiotic food supplement SYN‐53 has previously shown efficacy in managing allergic rhinoconjunctivitis (ARC), with its high bacterial diversity and dosage hypothesized as key drivers. This study on 166 subjects aimed to confirm this hypothesis by comparing the effects of SYN‐53, a low dose variant (SYN‐53‐LD), a low diversity variant (SYN‐4), and ...
Karl‐Christian Bergmann, Torsten Zuberbier   +1 more
wiley   +1 more source