Results 271 to 280 of about 80,269 (322)

Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu   +4 more
wiley   +1 more source

The role of gut microbiota in chronic intestinal pseudo-obstruction: exploring fecal microbiota transplantation as a treatment option. [PDF]

open access: yesGut Microbes
De Palma G   +15 more
europepmc   +1 more source

Stem Cell Therapy for Inflammatory Diseases: Progress, Challenges, and Future Directions

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Stem cells offer multifaceted therapeutic approaches for inflammatory diseases, each exhibiting distinct therapeutic properties. Hematopoietic stem cells, primarily through hematopoietic stem cell transplantation (HSCT), can effectively remodel the immune environment, showing particular promise in treating genetically linked cases.
Chen Wu   +4 more
wiley   +1 more source

Fecal Microbiota Transplantation in Refractory Immune-Mediated Colitis: Case Series and Review of the Literature. [PDF]

open access: yesPharmaceuticals (Basel)
Golčić M   +16 more
europepmc   +1 more source

Role of Acid‐Sensing Ion Channels 1a in the Regulation of Obesity and the Gut Microbiota

open access: yesObesity, Volume 34, Issue 2, Page 372-381, February 2026.
ABSTRACT Objective Acid‐sensing ion channels are proton‐activated ion channels predominantly found in the nervous system. They are well known to affect metabolic and neurological health, yet their role in obesity and gut physiology remains unclear. This study investigates how systemic deletion of Asic1a influences obesity, metabolic, and gut‐based ...
Jane Shearer   +7 more
wiley   +1 more source

Gut Microbiome Dysbiosis is Associated With Human T‐Lymphotropic Virus Type 1 (HTLV‐1) Infection and Disease Progression to HTLV‐1‐Associated Myelopathy/Tropical Spastic Paraparesis: A Cross‐Sectional Study

open access: yesSmart Medicine, Volume 5, Issue 1, February 2026.
We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Lorena Abreu Fernandes   +8 more
wiley   +1 more source

Fecal microbiota transplantation is a promising therapy for kidney diseases. [PDF]

open access: yesFront Med (Lausanne)
Zhang J   +5 more
europepmc   +1 more source

Aging of the Hematopoietic System: Mechanisms, Consequences, and Systemic Interactions

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Hematopoietic aging arises from intrinsic stem‐cell decline and bone‐marrow niche dysfunction, leading to myeloid skewing, immunosenescence, and clonal hematopoiesis. These changes drive systemic inflammation and multi‐organ disease, which in turn further disrupt the bone‐marrow niche and hematopoietic stem cell (HSC) function, creating a vicious cycle
Masashi Miyawaki   +3 more
wiley   +1 more source

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