Results 131 to 140 of about 207,535 (267)

Exosome‐mediated gut–brain axis signaling in neurodegenerative diseases: Mechanisms, experimental evidence, and therapeutic perspectives—A narrative review

Animal Models and Experimental Medicine, EarlyView.
The gut–brain axis is a bidirectional communication network between the intestines and brain, mediated by gut microbiota and exosomes, that regulates neuroinflammation, protein aggregation, and neuronal health processes central to neurodegenerative diseases.
Waheeb Sami Aggad, Rakesh Ghosh, Hailah M. Almohaimeed, Zuhair M. Mohammedsaleh, Fayez M. Saleh, Amany I. Almars, S. Renuka Jyothi, Rajashree Panigrahi, Ajoy Kumer, Bikram Dhara   +9 more
wiley   +1 more source

A Phase 1 Microtracer Study Evaluating the Mass Balance, Excretion, and Pharmacokinetics of Osivelotor in Healthy Participants. [PDF]

Clin Transl Sci
Zimmerman EI, Callegari E, Sharma R, Adenola A, Volpe J, Seetharaman K, Zhang C, Duchin K, Walker GS.   +8 more
europepmc   +1 more source

Identification and validation of fecal complement component 3 and fibronectin as potential biomarkers for monitoring disease activity in ulcerative colitis based on a mouse model

Animal Models and Experimental Medicine, EarlyView.
This study demonstrated elevated levels of fecal component 3 (C3) and fibronectin (FN) in an ulcerative colitis (UC) mouse model. Importantly, fecal C3 exhibited a stronger correlation with disease activity than the clinically used fecal calprotectin (FC).
Yangyun Guo, Ziheng Yan, Jingyu Ye, Ruifu Yang, Yajun Song, Hui Yue, Yong Zhao   +6 more
wiley   +1 more source

Inter-laboratory optimization for the detection of <i>Campylobacter jejuni</i> in canine fecal samples using <i>gyrA</i> PCR. [PDF]

J Vet Diagn Invest
Lawhon SD, Cummings KJ, Wu J, Yang CY, Whipple N, Prarat Koscielny M, Lindemann S, Kiener S, Kmet M, Reddy R, Goodman LB, Franklin-Guild RJ, Sams K, Cronk B, Cui J, Lawrence K, Zhang Q, Zhang Y, Ensley S, Olsen K, Tomaszewski J, Shen Z, Zhang S, Dasgupta S, Mann S, Patil A, Thakur S, Rankin SC, Ruesch L, Garcia-Fernandez N, Guag J, Nemser SM, Reimschuessel R.   +32 more
europepmc   +1 more source

Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson's Disease

Annals of Neurology, EarlyView.
We conducted a nested case‐control study within the Nurses’ Health Study and the Health Professionals Follow‐up Study to examine the role of the gut virome (GV) in Parkinson's disease (PD). We applied a novel metagenomic virome profiling approach, Bioinformatic Application for Quantification and Labeling of Viral taxonomy (BAQLaVa), to prospectively ...
Deepika Dinesh, Xochitl C. Morgan, Jordan Jensen, Kjetil Bjornevik, Michael A. Schwarzschild, Alberto Ascherio, Curtis Huttenhower, Natalia Palacios   +7 more
wiley   +1 more source

Behavioral Selection of Coprophagy in an Arid-Adapted Herbivore: Does a Compatibility-Risk Gradient Shape Selective Coprophagy? [PDF]

Ecol Evol
Moeller C, Henke SE, Rideout-Hanzak S, Eversole CB.   +3 more
europepmc   +1 more source

Prion shedding is reduced by chronic wasting disease vaccination. [PDF]

PLoS Pathog
Ahmed-Hassan H, Abdelaziz D, Cheng YC, Low K, Phan S, Kruger B, Dalton CS, Kaczmarczyk L, Jackson WS, Gilch S, Schätzl HM.   +10 more
europepmc   +1 more source

Fecal ACE and ACE2 Activities Reflect Intestinal Shedding and Microbiota Modulation of Renin-Angiotensin System. [PDF]

Biology (Basel)
Ferreira-Duarte M, Quintas C, Bom J, Ribeiro AL, Pereira M, Bader M, Alenina N, Bernstein KE, Bernstein EA, Sousa T, Magro F, Duarte-Araújo M, Oliveira LCG, Casarini DE, Morato M.   +14 more
europepmc   +1 more source

Synergistic Advanced Oxidation and Physicochemical Treatment Strategies for Antibiotic Removal and Resistance Mitigation in Water

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley   +1 more source

The Relationships of Season, Climate, Habitat, and Sex Variables With Fecal Cortisol, Progesterone, and Testosterone Metabolite Concentrations in Roe Deer. [PDF]

Ecol Evol
Amininasab SM, Pirsaraei ZA, Bisheh AY.
europepmc   +1 more source