Results 141 to 150 of about 241,153 (312)

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

Advanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou, Lei Zhang, Xingyu Cai, Jiajia Su, Guangyu Dai, Xue Chen, Hanming Wang, Jia Hua, Jianping Liu, Chunmeng Sun, Xiancheng Chen, Erhao Wang, Wenli Zhang   +12 more
wiley   +1 more source

Validation of a commercial ELISA kit to measure 11-oxoetiocholanolone in equine and bovine feces

Feces are a noninvasive and easily collectible matrix that may help determine cumulative hormone metabolite concentrations over medium-to-long times. To date, 11-oxoetiocholanolone, an important metabolite of cortisol, has been measured in equine and ...
Prandi A., Peric T., Pividori I., Comin A., Zoratti A., Comin, Antonella, Pividori, Isabella, Zoratti, A., Pividori, I., Peric, T., Prandi, Alberto, Prandi, A., Zoratti, Aloma, Peric, Tanja   +13 more
core   +1 more source

Correlations between glycemic control and organic acids in feces.

, 2019
Correlation between (A) HbA1c and propionic acids in feces (r = -0.262, P = 0.004, n = 118), (B) HbA1c and acetic acids in feces (r = -0.196, P = 0.037, n = 118), (C) HbA1c and butyric acids in feces (r = -0.247, P = 0.009, n = 110) and (D) fasting blood
Hirotaka Watada (131439), Shoko Tamaki (7406480), Junko Sato (4640326), Yuichiro Yamashiro (3419936), Yoshifumi Tamura (219220), Takuya Takahashi (161915), Takashi Asahara (161918), Akio Kanazawa (3821599), Satoshi Matsumoto (830797)   +8 more
core   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

ESBL-Type and AmpC-Type Beta-Lactamases in Third Generation Cephalosporin-Resistant Enterobacterales Isolated from Animal Feces in Madagascar

Animals
Third generation cephalosporin-resistant (3GCR) Enterobacterales are known to be prevalent in Madagascar, with high colonization or infection rates in particular in Madagascan patients.
Ulrich Schotte, Julian Ehlers, Johanna Nieter, Raphaël Rakotozandrindrainy, Silver A. Wolf, Torsten Semmler, Hagen Frickmann, Sven Poppert, Christa Ewers   +8 more
doaj   +1 more source

C. elegans-slug feces experiment

, 2015
Experimental analysis of the ability of the model nematode to survive the passage of Arion slugs and be excreted with the slug feces. Single slugs of the genus Arion (first column of table) were exposed to red fluorescent C.
Hinrich Schulenburg (74712), Ruben Joseph Hermann (3275268), Rebecca Schalkowski (3275271), Camilo Barbosa (3275274), Schalkowski, Rebecca, Barg, Mike-Christoph, Dirksen, Philipp, Schulenburg, Hinrich, Petersen, Carola, Mike-Christoph Barg (3275265), Barbosa, Camilo, Philipp Dirksen (3275262), Hermann, Ruben Joseph, Carola Petersen (3275277)   +13 more
core   +1 more source

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

Advanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng, Yingfei Zhang, Chong Wu, Qijia Duan, Mengqi Fan, Kuan Wang, Shirong Cai, Immihan Ceren Yasa   +7 more
wiley   +1 more source

Mycobacterium ulcerans in Possum Feces before Emergence in Humans, Australia

We describe emergence of Buruli ulcer in urban Geelong, Victoria, Australia, and examine timing and proximity of human cases to detection of Mycobacterium ulcerans DNA in possum feces. M.
Michael Muleme, Kim R. Blasdell, Eugene Athan, Anjana Karawita, Michael Dunn, Mohammad Akhtar Hussain, Naomi E. Clarke, Daniel P. O’Brien, Tiffany Pe, Jack Cornish, Ee Laine Tay, Victoria Boyd, Bridgette J. McNamara   +12 more
core   +2 more sources

Sonogenetics Nanomedicine Activates the cGAS‐STING Pathway for Immunotherapy of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song, Yan Liu, Shifeng Zhao, Cheng Zhu, Hongchang Guo, Jin Chang, Jun Kang   +6 more
wiley   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source