Results 231 to 240 of about 241,153 (312)

Bacterial backpacks for targeted delivery of piezoelectric nanoparticles to enhance sonodynamic immunotherapy

BMEMat, EarlyView.
Leveraging bacterial hypoxia targeting, KBTO NPs accumulate at the tumor site. Under the ultrasound irradiation, KBTO NPs produce reactive oxygen species to kill tumor cells and eliminate bacteria, preventing overgrowth and inflammation. The lysed bacteria act as antigens to trigger antitumor immunity and further enhanced by the immune checkpoint ...
Chongyang Liu, Haohui Zhu, Huaibin Yu, Xijun Zhang, Zhiqin Lei, Wenjing Xu, Xinyu Zhao, Ming Wu, Long Yang, Juanjuan Liu, Zhengbao Zha, Xinghui Si, Jianjun Yuan   +12 more
wiley   +1 more source

Microplastics in urban environments: The dog as a bioindicator of exposure and human gastrointestinal risk [PDF]

Biomedica
Martínez-Cepeda G, Ramos-Sarmiento D, Sailema-Rosado G, Sangache-Guamán A, Bustos-Chávez N, Salcán-Guamán H, Fernández-Morales M, Díaz-Cevallos L.   +7 more
europepmc   +1 more source

A bioinspired catalytic nanoplatform for ferroptosis‐immunotherapy synergy in metastatic cancer

BMEMat, EarlyView.
The bioinspired nanoplatform MnMSN@MnP‐PEG co‐delivers manganese peroxidase and manganese ions to synergistically induce immunogenic ferroptosis and activate the cGAS‐STING pathway, eliciting potent antitumor immunity against primary and metastatic tumors.
Panpan Xue, Hai Cai, Ying Sun, Yaxin Ma, Siyuan Liu, Jinying Zhu, Yan Chen, Xuemei Zeng, Shuangqian Yan   +8 more
wiley   +1 more source

Black-Tailed Godwits Eat Animal and Plant Material at a Key Non-Breeding Site at the Overlap of Two Asian Flyways. [PDF]

Ecol Evol
Das DK, Khandakar N, Ali MS, Vansteelant WMG, El-Hacen EM, Piersma T.   +5 more
europepmc   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Mass balance, excretion, and pharmacokinetics of a single oral dose of [¹⁴C]pixavir marboxil in healthy Chinese male participants. [PDF]

Front Pharmacol
Zhao C, Yang Y, Liu G, Qian L, Liu Y, Tsai CY, Chang LW, Chen Q, Qian H, Jia J, Liu Y.   +10 more
europepmc   +1 more source

Probiotic spore‐based bioresponsive drug delivery for reversing inflammatory bowel disease and its associated anxiety and depression

BMEMat, EarlyView.
A probiotic spore‐based drug delivery system (BCS‐Que@ApNPs) provides excellent targeted delivery, bioresponsive drug release, and long‐term retention (over 48 h), making it suitable for oral treatment of inflammatory bowel disease and its associated anxiety and depression.
Qingling Song, Beiyang Xue, Yao Li, Chuangxi Zhou, Junfei Yang, Yunfei Li, Lingwen Ding, Yun Zhang, Hongjuan Zhao, Lei Wang   +9 more
wiley   +1 more source

Sex-Dependent Lipidomic Remodeling in Plasma and Feces Following High-Fat Diet Intake in Adult Rats. [PDF]

Nutrients
González-Las Heras S, Forsten R, Rio-Aige K, Castell M, Costabile A, Melgar S, Pérez-Cano FJ, Massot-Cladera M, Rodríguez-Lagunas MJ.   +8 more
europepmc   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source