Results 181 to 190 of about 47,623 (197)

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Effectiveness of an Educational Intervention With Home Visits and Telephone Follow-Up on Knowledge and Quality of Life in Patients With Heart Failure: A Randomized Clinical Trial. [PDF]

Nurs Health Sci
de Goes Marques CR, Santos ES, da Silva LS, de Castro Guimarães EA, Dos Santos TG, Dos Santos Sales VB, Silva WA, Sousa ACS.   +7 more
europepmc   +1 more source

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

The Epidemiological Scenario of Human Leptospirosis in Brazil from 2015 to 2024. [PDF]

Epidemiologia (Basel)
Fernandes GSC, Azevedo BOP, Damiano DK, Lima MVR, Macena PP, Teixeira AF, Barazzone GC, Nascimento ALTO, Lopes APY.   +8 more
europepmc   +1 more source

Tailored Covalent Organic Frameworks Enable the Encapsulation of Living Cells to Produce Rare Ginsenoside

Advanced Science, EarlyView.
This work reports the in situ fabrication of Escherichia coli@covalent organic frameworks (E. coli@COFs) in phosphate‐buffered saline. The COFs form an exoskeleton on E. coli, protecting intracellular β‐glucosidase (Ssbgl) while enhancing mass transfer.
Fengmei Liu, Shan Zhang, Shanrong Wei, Ziye Xing, Hongming He, Xiao Liang, Quanshun Li   +6 more
wiley   +1 more source

Health education needs of the Brazilian population with rheumatoid arthritis: mixed-methods cross-sectional study. [PDF]

Rheumatol Int
Prando BC, Albano TM, Dos Santos GB, Gonçalves GV, da Silva Serrão PRM.   +4 more
europepmc   +1 more source

TiO6 as a Compensatory Structural Unit in Co‐Free, High‐Ni Layered Oxide for Durable Lithium‐Ion Batteries

Advanced Science, EarlyView.
Ti substitution stabilizes Co‐free high‐Ni layered oxides through both structural and electronic effects. TiO6 octahedra act as compensatory structural units that help interrupt cooperative Jahn–Teller distortion and suppress detrimental phase transitions, while the electron‐withdrawing inductive effect of Ti stabilizes the oxygen lattice. As a result,
Bixian Ying, Zhenjie Teng, Jun Wang, Honghong Tian, Charlotte von Petersdorff‐Campen, Rommel T. Tolla, Iuliia Mikulska, Linus Voigt, Sascha Nowak, Verena Naber, Alexander Schökel, Yuanming Liu, Michael Merz, Peter Nagel, Stefan Schuppler, Katja Frenzel, Adrian Jonas, Lena Mathies, Martin Winter, Karin Kleiner   +19 more
wiley   +1 more source

Poor knot security when closing running sutures with three threads. [PDF]

Facts Views Vis Obgyn
Romeo A, Giarola M, Kondo W, Amro B, Ussia A, Adamyan L, Wattiez A, Koninckx PR.   +7 more
europepmc   +1 more source

Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis

Advanced Science, EarlyView.
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu, Shuai Zhang, Jie Zhang, Zhen Tian, Yuanbo Xue, Ling Yang, Jun Xu, Guirong Wang   +7 more
wiley   +1 more source

Health of Black Populations and Sexual and Gender Minorities in Health Education: A Scoping Review. [PDF]

Nurs Rep
Silva BPD, de Carvalho Nagliate P, Brito GDS, Bonfim Sousa de Queiroz D, de Morais E Oliveira AP, Alves Rozendo C, Santos Dos Anjos Cardoso D, Paulino GB, Conceição YOND, Luz RSD, Rocha FM, Marques D, Kassada DS, Abeldaño Zuñiga RA, Pereira da Costa PC, Saidel MGB, Sodré de Souza E, Santos DS.   +17 more
europepmc   +1 more source