Results 21 to 30 of about 47,623 (197)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Comparative analysis of the content and specifications of the state educational standard and federal state educational standards for decorative and applied creativity

open access: yesВестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2019
The relevance of the topic under study is caused by changes in the sphere of legal regulation of higher education, which require deep thinking from all participants in the educational process.
Ekaterina O. Kunyaevа
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Model of sociology training introduced by the fourthgeneration Federal State Educational Standard

open access: yesRUDN journal of Sociology
Today a new level-system of higher education is formed in Russia through significant changes that meet the new requirements for specialists in economics, social sectors, and all spheres of public life. The new system is to incorporate the developments of
L. V Temnova
doaj   +1 more source

THE PROBLEMS OF IMPLEMENTING THE FEDERAL STATE EDUCATIONAL STANDARDS RELATED TO THE SECONDARY VOCATIONAL EDUCATION

open access: yesОбразование и наука, 2015
The paper considers the inner problems of secondary vocational education, activated by implementation of the new competence oriented educational standards.
B. I. Shemet, O. B. Shemet
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

PROFESSIONAL STANDARD AND FEDERAL STATE EDUCATIONAL STANDARD FOR UNDERGRADUATE PROGRAMS

open access: yesВысшее образование в России, 2018
.Undergraduate educational programs making on the basis of professional standards compliance does not meet the strategic goal of vocational education system reforming – training personnel capable of making modern competitive products and services ...
V. A. PROKHOROV
doaj  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

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