Results 41 to 50 of about 1,052,146 (304)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Growth performance, bone mineralization, and mineral transporter gene expression in broiler chickens fed varying non-phytate phosphorus levels at a fixed calcium to non-phytate phosphorus ratio

Poultry Science
This study investigated the effects of dietary non-phytate phosphorus (NPP) levels on growth performance, bone mineralization, and mineral transporting gene expression in broilers (1–21 d), under a 2:1 calcium (Ca)-to-NPP ratio.
Jincheng Han, Yan Zhang, Bingbing Ma, Yu Zhou, Mengyue Chen, Hongxia Qu, Li Xi, Guanhua Chen, Chunyang Niu, Chuanxin Shi, Guangli Yang, Zhixiang Wang   +11 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Microbial feed additive

, 2012
The invention provides a feed additive containing the microorganism Kluyveromyces marxianus WJ1 wherein the feed additive is useful for improved rumen fermentation in ruminant animals.
Nooraee, Seyed Eeman, Abdullah, Norhani, Alimon, Abdul Razak, Ho, Yin Wan   +3 more
core   +1 more source

MAPK signaling pathway participates in the regulation of intestinal phosphorus and calcium absorption in broiler chickens via 1,25-dihydroxyvitamin D3

Poultry Science
: Four experiments were performed to investigate the role of the mitogen-activated protein kinase (MAPK) signaling pathway in intestinal absorption of phosphorus (P) and calcium (Ca) in broiler chickens.
Jincheng Han, Xianliang Lv, Lei He, Mengyuan Liu, Hongxia Qu, Li Xi, Liao Zhang, Bingbing Ma, Chuanxin Shi, Guangli Yang, Zhixiang Wang   +10 more
doaj   +1 more source

Safety and efficacy of a feed additive consisting of a dry grape extract (Nor‐Grape® α) for all avian species (Nor‐Feed S.A.S.)

EFSA Journal, 2023
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a feed additive consisting of a dry grape extract (Nor‐Grape® α) as a zootechnical feed additive, functional group ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Mojca Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Paul Brantom, Andrew Chesson, Giovanna Martelli, Johannes Westendorf, Jordi Ortuño, Paola Manini, Fabiola Pizzo   +24 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Safety and efficacy of the feed additive consisting of Vitamin B2/Riboflavin produced by Eremothecium ashbyi CCTCCM 2019833 for all animal species (Hubei Guangji Pharmaceutical Co., Ltd)

EFSA Journal, 2021
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the feed additive Vitamin B2/Riboflavin produced by Eremothecium ashbyi CCTCCM ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Mojca Fašmon Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Paul Georges Brantom, Pier Sandro Cocconcelli, Boet Glandorf, Lieve Herman, Miguel Prieto Maradona, Maria Saarela, Kettil Svensson, Luca Tosti, Jaume Galobart, Paola Manini, Elisa Pettenati, Fabiola Pizzo, Jordi Tarrés‐Call, Montserrat Anguita   +31 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Dietary non-phytate phosphorus and phytase interaction affects growth performance, mineral transportation and metabolism in broiler chickens

Poultry Science
The interaction effects of dietary non-phytate phosphorus (NPP) and phytase on growth performance, mineral metabolism, and gene expressions of mineral transporters in broilers duodenum and kidney (0-3 weeks) were studied. The levels of NPP (0.45 %, 0.35 %
Bingbing Ma, Yan Zhang, Mengyuan Liu, Chuanxin Shi, Yu Zhou, Mengyue Chen, Yuchun Chang, Hongxia Qu, Liao Zhang, Chunmei Zhang, Guanhua Chen, Jincheng Han   +11 more
doaj   +1 more source