Results 31 to 40 of about 2,517,379 (295)

Control of tissue homeostasis, tumorigenesis, and degeneration by coupled bidirectional bistable switches.

open access: yesPLoS Computational Biology, 2021
The Hippo-YAP/TAZ signaling pathway plays a critical role in tissue homeostasis, tumorigenesis, and degeneration disorders. The regulation of YAP/TAZ levels is controlled by a complex regulatory network, where several feedback loops have been identified.
Diego Barra Avila   +2 more
doaj   +1 more source

Tubuloglomerular feedback: Its physiological and pathophysiological significance [PDF]

open access: yesKidney International, 1998
The mammalian nephron has a unique structure called juxtaglomerular apparatus (JGA); the primary function of the JGA includes tubuloglomerular feedback. Why is such a structure necessary? Analyses of available data strongly suggest that JGA has evolved to provide a fine tuning of the autoregulation of glomerular hemodynamics and high glomerular ...
openaire   +2 more sources

Predictive feedback control and Fitts' law [PDF]

open access: yes, 2008
Fitts’ law is a well established empirical formula, known for encapsulating the “speed-accuracy trade-off”. For discrete, manual movements from a starting location to a target, Fitts’ law relates movement duration to the distance moved and target size ...
Loram, I.   +5 more
core   +1 more source

Evaluation of a vibrotactile feedback device for spatial guidance [PDF]

open access: yes, 2011
In the present study, a vibrotactile feedback device for spatial guidance was evaluated in a tracking task paradigm. Participants (N = 18) had to translate and rotate virtual objects according to the vibrotactile vs.
Weber, Bernhard   +14 more
core   +1 more source

Physiological Positive Feedback Mechanisms

open access: yesAmerican Journal of Biomedical Sciences, 2011
In positive feedback mechanisms, the response to a stimulus does not stop or reverse it but instead keeps the sequence of events going up. At first glance, this would appear to be a counter to the principle of homeostasis, since a positive feedback loop has no obvious means of stopping.
openaire   +1 more source

Multimodal measurements enhance insights into emotional responses to immediate feedback

open access: yesFrontiers in Psychology
Adaptive learning technologies often provide students with immediate feedback on task performance. This feedback can elicit various emotional responses, which, in turn, influence learning. Most recent studies capture these emotions by single data streams,
Anne Horvers   +4 more
doaj   +1 more source

The feeling of agency: Empirical indicators for a pre-reflective level of action awareness

open access: yesFrontiers in Psychology, 2011
The sense of agency has been defined as the sense that I am the author of my own actions. This sense, however, is usually not reflected upon but instead pre-reflectively experienced.
Nicole eDavid   +4 more
doaj   +1 more source

A balance equation determines a switch in neuronal excitability. [PDF]

open access: yesPLoS Computational Biology, 2013
We use the qualitative insight of a planar neuronal phase portrait to detect an excitability switch in arbitrary conductance-based models from a simple mathematical condition. The condition expresses a balance between ion channels that provide a negative
Alessio Franci   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Feedback systems as interferers in perfectionism: a systematic literature review

open access: yesFrontiers in Psychiatry
BackgroundPerfectionism is a multidimensional construct characterized by the striving for exceptionally high standards and critical self-evaluation. It can manifest in both adaptive and maladaptive forms.
Adel Bartos   +4 more
doaj   +1 more source

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