Results 41 to 50 of about 4,796 (263)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Linear Bandits with Feature Feedback

Proceedings of the AAAI Conference on Artificial Intelligence, 2020
This paper explores a new form of the linear bandit problem in which the algorithm receives the usual stochastic rewards as well as stochastic feedback about which features are relevant to the rewards, the latter feedback being the novel aspect. The focus of this paper is the development of new theory and algorithms for linear bandits with feature ...
Urvashi Oswal, Aniruddha Bhargava, Robert D. Nowak   +2 more
openaire   +3 more sources

Robust Feedback Linearization Based Disturbance Observer Control of Quadrotor UAV

IEEE Access
This paper presents a novel Robust Feedback Linearization (RFBL) controller for Quadrotor Unmanned Aerial Vehicle (UAV) when subjected to external disturbances.
Mohammad Sadiq, Rameez Hayat, Kamran Zeb, Ahmed Al-Durra, Zahid Ullah   +4 more
doaj   +1 more source

A nonlinear optimal control approach for the pulping process of paper mills

IET Collaborative Intelligent Manufacturing, 2021
The mechanical pulping process is non‐linear and multivariable. To solve the related control problem, the dynamic model of the pulping process undergoes first approximate linearization around a temporary operating point which is updated at each iteration
G. Rigatos, M. Abbaszadeh, G. Cuccurullo, P. Siano   +3 more
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Design of an Adaptive-Neural Network Attitude Controller of a Satellite using Reaction Wheels

Journal of Applied and Computational Mechanics, 2015
In this paper, an adaptive attitude control algorithm is developed based on neural network for a satellite using four reaction wheels in a tetrahedron configuration.
Abbas Ajorkar, Alireza Fazlyab, Farhad Fani saberi, Mansour Kabganian   +3 more
doaj   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Feedback linearization and equivalent-disturbance compensation control strategy for piezoelectric stage

Nanotechnology and Precision Engineering
Piezoelectric stages use piezoelectric actuators and flexure hinges as driving and amplifying mechanisms, respectively. These systems have high positioning accuracy and high-frequency responses, and they are widely used in various precision/ultra ...
Tao Huang, Yingbin Wang, Zhihong Luo, Huajun Cao, Guibao Tao, Mingxiang Ling   +5 more
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Generalized Quadratic Linearization of Machine Models

Journal of Control Science and Engineering, 2011
In the exact linearization of involutive nonlinear system models, the issue of singularity needs to be addressed in practical applications. The approximate linearization technique due to Krener, based on Taylor series expansion, apart from being ...
Parvathy Ayalur Krishnamoorthy, Kamaraj Vijayarajan, Devanathan Rajagopalan   +2 more
doaj   +1 more source