Results 91 to 100 of about 1,278,700 (293)

Performance assessment and diagnosis of refinery control loops [PDF]

, 1998
This paper discusses the application of control loop performance assessment (Desborough and Harris, 1992) in a refinery setting. In a large process it is not feasible to tailor the parameters of the algorithm to every individual control loop. A procedure
Oettinger, M, Fedenczuk, P, Thornhill, NF   +2 more
core  

Nurse TH adoption feedback loops.

, 2020
Nurse TH adoption feedback loops.
Nicos Maglaveras (8537733), Casandra Grundstrom (8537727), Stefan Winter (258663), Ioanna Chouvarda (6170747), Katerina Lourida (8537730), Violeta Gaveikaite (8537724), Rita Priori (5562686)   +6 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Physicians TH adoption feedback loops.

, 2020
Physicians TH adoption feedback loops.
Nicos Maglaveras (8537733), Casandra Grundstrom (8537727), Stefan Winter (258663), Ioanna Chouvarda (6170747), Katerina Lourida (8537730), Violeta Gaveikaite (8537724), Rita Priori (5562686)   +6 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

FEEDBACK SOBRE AUTOPERCEPCIONES. UNA ESTRATEGIA INSTITUCIONAL PARA EL EMPODERAMIENTO DE INGRESANTES EN INGENIERÍA. [PDF]

, 2014
Este trabajo forma parte de un proyecto institucional de mayor envergadura del que participamos como representantes del Laboratorio de Monitoreo de Inserción de Graduados de la Facultad de Ingeniería de la Universidad Nacional de Río Cuarto.
Chiecher, Analía Claudia, Paoloni, Paola Verónica Rita   +1 more
core  

Physiotherapist TH adoption feedback loops.

, 2020
Physiotherapist TH adoption feedback loops.
Nicos Maglaveras (8537733), Casandra Grundstrom (8537727), Stefan Winter (258663), Ioanna Chouvarda (6170747), Katerina Lourida (8537730), Violeta Gaveikaite (8537724), Rita Priori (5562686)   +6 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Dynamic Modeling and Analysis of the Cross-Talk between Insulin/AKT and MAPK/ERK Signaling Pathways.

PLoS ONE, 2016
Feedback loops play a key role in the regulation of the complex interactions in signal transduction networks. By studying the network of interactions among the biomolecules present in signaling pathways at the systems level, it is possible to understand ...
Yaman Arkun
doaj   +1 more source

Dual delayed feedback provides sensitivity and robustness to the NF-κB signaling module.

PLoS Computational Biology, 2013
Many cellular stress-responsive signaling systems exhibit highly dynamic behavior with oscillatory features mediated by delayed negative feedback loops.
Diane M Longo, Jangir Selimkhanov, Jeffrey D Kearns, Jeff Hasty, Alexander Hoffmann, Lev S Tsimring   +5 more
doaj   +1 more source