Results 91 to 100 of about 89,082 (306)

Crosstalk Between CTSB+ Glioblastoma Cells and S100A10+ Macrophages: A Self‐Reinforcing Circuit Promotes Immune Evasion and Limits Response to Immunotherapy

open access: yesAdvanced Science, EarlyView.
In glioblastoma, M2‐polarized macrophages secrete IL‐6, which activates STAT3 signaling in tumor cells to upregulate CTSB. Tumor‐derived CTSB binds the C‐terminus of macrophage S100A10, reinforcing M2 polarization and further IL‐6 secretion, thereby establishing a feedforward IL‐6/STAT3/CTSB/S100A10 loop. This cascade drives tumor growth, invasion, and
Hao Zhang   +11 more
wiley   +1 more source

Feedforward neural networks with constrained weights [PDF]

open access: yes
The conventional multilayer feedforward network having continuous-weights is expensive to implement in digital hardware. Two new types of networks are proposed which lend themselves to cost-effective implementations in hardware and have a fast forward ...
Khan, Altaf Hamid
core  

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

open access: yesAdvanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu   +10 more
wiley   +1 more source

Biofeedback and Feedforward in Telerobotics Control

open access: yes, 1994
Biofeedback and Feedforward in Telerobotics ...
COSMI, Francesca   +3 more
core  

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

open access: yesAdvanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan   +16 more
wiley   +1 more source

Development of a Path Tracker Based on a 4WS Vehicle for Low-Speed Automated Driving Systems

open access: yesApplied Sciences
With the increasing demand for various autonomous driving services in urban environments, low-speed autonomous vehicles, such as autonomous shuttles and purpose-built vehicles, equipped with enhanced driving characteristics suitable for urban roads ...
Heung-Sik Park, Moon-Sik Kim
doaj   +1 more source

Public feedback - but personal feedforward?

open access: yesJournal of Learning Development in Higher Education, 2012
People can learn by considering and understanding examples. With assistance, students should see and appreciate in examples strengths on which they can build, and weaknesses which they should minimise. So feedback and feedforward to students can usefully
John Cowan, YiChing Jean Chiu
doaj   +1 more source

Flexible linearity profile amplifier for software defined applications [PDF]

open access: yes, 2002
A highly linear Low Noise Amplifier (LNA) using a flexible feedforward linearisation scheme is described. The wideband LNA is designed for use in the frequency spectrum between 1 and 2GHz.
Watkins, GT, Warr, PA
core  

Model-based feedforward for motion systems [PDF]

open access: yes, 2003
This paper considers model-based feedforward for motion systems. The proposed feedforward controller consists of an acceleration feedforward part and an inverse dynamics model of flexible modes.
Wal, van de, M.M.J.   +8 more
core   +2 more sources

Osseoperceptive EMG Feedback Improves Grasp Force Control in Myoelectric Prosthetic Hands

open access: yesAdvanced Science, EarlyView.
Osseoperception is explored as a non‐invasive pathway for delivering sensory feedback in myoelectric prosthetic control. By encoding the user's electromyographic (EMG) signal through bone‐conducted stimulation, this approach enables predictive grasp force regulation.
Cristian Felipe Blanco‐Diaz   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy