Results 41 to 50 of about 43,296 (240)

Providing alternative fuel for the brain in anorexia nervosa: a review of the literature on ketones and their effects on metabolism and the brain

Translational Psychiatry
Recent genetic findings have highlighted the importance of metabolic factors in contributing to risk for anorexia nervosa. The treatment of anorexia nervosa, however, has largely not yet attempted to modulate metabolic pathways, given that knowledge and ...
Nadia Micali, Maria Consolata Miletta, Christoffer Clemmensen, Edoardo Pappaianni, Francois Lazeyras, Bernard Cuenoud, Carmen Sandi   +6 more
doaj   +1 more source

Investigation of the relationship between type 2 diabetes risk and night eating behavior

Medicine Science, 2020
The aim of this study is to determine the prevalence of night-eating behavior and risk of undiagnosed type 2 diabetes in the community and to investigate a relationship between them.
Serdar Derya, Burcu Kayhan Tetik, Burak Mete   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Update on Major Eating Disorders (Anorexia Nervosa and Bulimia): A Topic Review

Vertex Revista Argentina de Psiquiatría
Eating Disorders are mental illnesses with potentially life-threatening consequences and with a challenging treatment. The most common types are Anorexia Nervosa, Bulimia Nervosa, and Binge Eating Disorder.
Mateo López-Trujillo, Sara María Gómez-Restrepo, Sebastián Hoyos-Sanabria, Valentina Vela-Arbeláez   +3 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Pregorexia: a systematic review and meta-analysis on the constructs of body image dissatisfaction and eating disturbances by gestational age in the peripartum

Eating and Weight Disorders, 2023
Purpose Pregorexia is a phenomenon posited to occur in the peripartum, characterized by an attempt to counter pregnancy’s physiological changes in body shape through reduced calorie intake or increased physical activity.
Livio Tarchi, Giuseppe Pierpaolo Merola, Giulia Selvi, Eleonora Caprara, Vincenzo Pecoraro, Emanuele Cassioli, Eleonora Rossi, Felice Petraglia, Valdo Ricca, Giovanni Castellini   +9 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Online multidisciplinary treatment of binge eating disorder in people with high weight: a case series study

Journal of Eating Disorders, 2023
Background Binge eating disorder (BED) is the most frequent eating behavior among the general population (Guerdjikova in Med Clin 103:669–680, 2019). Many studies on interventions and BED treatments have been carried out in the United States and Europe ...
Mariana Valdez-Aguilar, Rosalia Vazquez-Arevalo, Xóchitl López-Aguilar, Ana Olivia Ruíz Martínez, Magda Rosinska, Juan Manuel Mancilla-Díaz   +5 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source