Results 61 to 70 of about 128,415 (288)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Comorbidity between psychosis and eating disorders: a systematic review

Journal of Eating Disorders
Background Comorbidity has been reported between eating disorders and psychotic illnesses such as schizophrenia, and several hypotheses regarding their relationship have been proposed.
Oliver Rumle Hovmand, Linda Lloyd Hughes, Celeste Mary Egtved, Sidse M. Arnfred   +3 more
doaj   +1 more source

\u3cem\u3eN\u3c/em\u3e-acetylcysteine Decreases Binge Eating in a Rodent Model [PDF]

, 2016
Binge-eating behavior involves rapid consumption of highly palatable foods leading to increased weight gain. Feeding in binge disorders resembles other compulsive behaviors, many of which are responsive to N-acetylcysteine (NAC), which is a cysteine ...
Baker, David A., Choi, Sujean, Frenkel, M. M., Hurley, M. M., Maunze, Brian, Resch, Jon M.   +5 more
core   +1 more source

Impact of Sleep and Circadian Disruption on Energy Balance and Diabetes: A Summary of Workshop Discussions [PDF]

, 2015
A workshop was held at the National Institute for Diabetes and Digestive and Kidney Diseases with a focus on the impact of sleep and circadian disruption on energy balance and diabetes.
Arble, Deanna M, Bass, Joseph, Behn, Cecilia Diniz, Butler, Matthew P, Challet, Etienne, Czeisler, Charles, Depner, Christopher M, Elmquist, Joel, Franken, Paul, Grandner, Michael A, Hanlon, Erin C, Joyner, Michael J, Karatsoreos, Ilia, Keene, Alex C, Kern, Philip A, Klein, Samuel, Morris, Christopher J, Pack, Allan I, Panda, Satchidananda, Ptacek, Louis J, Punjabi, Naresh M, Sassone-Corsi, Paolo, Saxena, Richa, Scheer, Frank A, Scheer, Frank A, Seaquest, Elizabeth R, Thimgan, Matthew S, Van Cauter, Eve, Wright, Kenneth P   +28 more
core   +4 more sources

The role of family relationships in eating disorders in adolescents: a narrative review [PDF]

, 2020
: Background: Adolescents’eatingdisordershavebeenexploredthroughvariousconceptual andempiricalmodels. Onlyrecently,scientificliteratureinthisareahasmorespecificallyinvestigated theroleofrelationships,withparticularattentiontofamilyfunctioning.
Luca Cerniglia, Michela Erriu, Silvia Cimino   +2 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Providing alternative fuel for the brain in anorexia nervosa: a review of the literature on ketones and their effects on metabolism and the brain

Translational Psychiatry
Recent genetic findings have highlighted the importance of metabolic factors in contributing to risk for anorexia nervosa. The treatment of anorexia nervosa, however, has largely not yet attempted to modulate metabolic pathways, given that knowledge and ...
Nadia Micali, Maria Consolata Miletta, Christoffer Clemmensen, Edoardo Pappaianni, Francois Lazeyras, Bernard Cuenoud, Carmen Sandi   +6 more
doaj   +1 more source

Pregorexia: a systematic review and meta-analysis on the constructs of body image dissatisfaction and eating disturbances by gestational age in the peripartum

Eating and Weight Disorders, 2023
Purpose Pregorexia is a phenomenon posited to occur in the peripartum, characterized by an attempt to counter pregnancy’s physiological changes in body shape through reduced calorie intake or increased physical activity.
Livio Tarchi, Giuseppe Pierpaolo Merola, Giulia Selvi, Eleonora Caprara, Vincenzo Pecoraro, Emanuele Cassioli, Eleonora Rossi, Felice Petraglia, Valdo Ricca, Giovanni Castellini   +9 more
doaj   +1 more source

Using group therapy to support eating disordered mothers with their children: the relevance for primary care [PDF]

, 2006
Eating disorders are a crippling and disabling condition. If they become chronic, the emotional, physical and social effects are substantial. The death rate is the highest of all psychiatric illnesses so the need to find prevention strategies is urgent ...
Barnett, Sarah, Buckroyd, Julia, Windle, Karen   +2 more
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source