Results 71 to 80 of about 126,479 (332)

Providing alternative fuel for the brain in anorexia nervosa: a review of the literature on ketones and their effects on metabolism and the brain

open access: yesTranslational Psychiatry
Recent genetic findings have highlighted the importance of metabolic factors in contributing to risk for anorexia nervosa. The treatment of anorexia nervosa, however, has largely not yet attempted to modulate metabolic pathways, given that knowledge and ...
Nadia Micali   +6 more
doaj   +1 more source

Metabolic Effects of Bariatric Surgery in Mouse Models of Circadian Disruption [PDF]

open access: yes, 2015
Background/Objectives: Mounting evidence supports a link between circadian disruption and metabolic disease. Humans with circadian disruption (for example, night-shift workers) have an increased risk of obesity and cardiometabolic diseases compared with ...
Arble, Deanna M.   +4 more
core   +3 more sources

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

Cannabis sativa and the endogenous cannabinoid system: therapeutic potential for appetite regulation [PDF]

open access: yes, 2011
The herb Cannabis sativa (C. sativa) has been used in China and on the Indian subcontinent for thousands of years as a medicine. However, since it was brought to the UK and then the rest of the western world in the late 19th century, its use has been a ...
Adams   +215 more
core   +3 more sources

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

open access: yesFEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro   +8 more
wiley   +1 more source

Unique considerations for the medical care of restrictive eating disorders in children and young adolescents

open access: yesJournal of Eating Disorders, 2023
Plain English summary Eating disorders are affecting increasingly younger patients, with ages of onset that now include children and young adolescents.
Anna B. Tanner
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Pancytopenia Associated with Avoidant Restrictive Food Intake Disorder: A Case Report

open access: yesRevista Portuguesa de Psiquiatria e Saúde Mental, 2020
Avoidant restrictive food intake disorder (ARFID) is one of the least clearly understood feeding and eating disorders, and there are no guidelines for its treatment. Patients with ARFID often present comorbid psychiatric disorders. The feeding and eating
Liliana Ferreira   +3 more
doaj   +1 more source

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