Results 221 to 230 of about 809,443 (296)

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt   +13 more
wiley   +1 more source

A Survey of Oncologists' Perceptions and Opinions Regarding Brain Imaging in Metastatic Renal Cell Carcinoma Within the UK. [PDF]

open access: yesCureus
Crosby BT   +9 more
europepmc   +1 more source

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari   +2 more
wiley   +1 more source

Key factors for implementing inhaler regimen switches in respiratory diseases: international expert consensus generated using a modified nominal group technique (NGT). [PDF]

open access: yesNPJ Prim Care Respir Med
Usmani OS   +14 more
europepmc   +1 more source

Pharmacomechanical catheter-directed thrombolysis for deep-vein thrombosis [PDF]

open access: yes, 2017
Blinder, M.   +7 more
core   +1 more source

Systematic review and scoring‐based selection of pharmacokinetic models for precision dosing of vancomycin in neonates and children

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
This systematic review identified 112 population pharmacokinetic models of vancomycin in neonates and children. To support rational model selection for model‐informed precision, we developed and applied expert‐driven, transparent criteria that integrate both methodological rigour and clinical relevance.
Zoë Vander Elst   +8 more
wiley   +1 more source

German Expert Consensus on Opioid-Induced Constipation (OIC): Recommendations and a Treatment Algorithm for Clinical Practice. [PDF]

open access: yesJ Clin Med
Wobbe B   +12 more
europepmc   +1 more source

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