Results 231 to 240 of about 5,972,941 (286)

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari, Caroline S. Copeland, Georgia C. Richards   +2 more
wiley   +1 more source

Short-Course Subcutaneous Immunotherapy With Mannan-Conjugated Birch Pollen Allergoids: Consistent Clinical and Immunological Improvements. [PDF]

Clin Transl Allergy
Raskopf E, Passamera S, Klimek L, Pfaar O, Neuhof C, Rybachuk A, Katzke N, Sahin H, Allekotte S, Mösges R, Day L, Subiza JL, Casanovas M, Cuevas M, Del Pozo S.   +14 more
europepmc   +1 more source

N‐acetylcysteine for non‐paracetamol‐induced acute liver failure in children: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Non‐surgical treatment of acute liver failure (ALF) is primarily supportive and depends on the underlying cause. While N‐acetylcysteine (NAC) is proven effective in paracetamol‐induced ALF, its potential benefits in non‐paracetamol ALF for paediatric patients remain unclear.
Alise D. E. de Groot, Désanka M. Stoppels, Arno R. Bourgonje, Willemien F. J. Hof, Martin C. J. Kneyber, Daan J. Touw, Henkjan J. Verkade, Paola Mian   +7 more
wiley   +1 more source

Patterns of central nervous system and leptomeningeal involvement in advanced breast cancer with invasive lobular histology: a large multicenter study with a focus on estrogen receptor-positive/HER2-negative disease. [PDF]

ESMO Open
Miglietta F, Vernieri C, Giarratano T, Griguolo G, Bottosso M, Vingiani A, Piacentini F, Cacciatore M, Botticelli A, Fotia G, Napolitano P, Landa G, Vernaci GM, Di Liso E, Casadei L, Palleschi D, Pruneri G, Dei Tos AP, Guarneri V, Dieci MV.   +19 more
europepmc   +1 more source

Trends in publicly subsidized and private access to GLP‐1 medicines indicated for type 2 diabetes in Australia, 2020–2025

British Journal of Clinical Pharmacology, EarlyView.
Aims GLP‐1 medicines provide substantial cardio‐renal benefits for type 2 diabetes (T2D) and are increasingly used for weight loss. Most high‐income countries subsidize access for T2D with restrictions; use outside of these restrictions occurs through private prescriptions. Despite strong consumer demand, the extent of private access to GLP‐1 medicines
Michael O. Falster, Juliana de Oliveira Costa, Tamara Y. Milder, Joanne Carson, Cade Shadbolt, Brendon L. Neuen, Clare Arnott, Andrew Wilson, Min Jun, Nicole Pratt, Sallie‐Anne Pearson   +10 more
wiley   +1 more source

Germline pharmacogenetic variants associated with trastuzumab deruxtecan-induced interstitial lung disease in advanced breast cancer: PROCURE project. [PDF]

ESMO Open
Arenas A, Saura C, Alva-Bianchi M, de Nicolás-Hernández J, Gion M, Cejalvo JM, Llabrés E, Cortés J, Falcón A, Pernas S, López de Sa A, Vidal M, Hinojo C, Curiel T, Cruz J, Martínez V, Cantos B, Echarri MJ, Gallegos I, Bueno C, Vargas AM, Escrivá-de-Romaní S, Fullana B, Cobos MA, Joval-Ramentol L, Ortiz-Heras P, Pascual T, Valdivia C, Villacampa G, Ciruelos E, Rodriguez-Antona C, Sánchez-Bayona R.   +31 more
europepmc   +1 more source

Long‐acting cabotegravir and rilpivirine in people with HIV receiving chronic anticoagulation: A real‐world case series

British Journal of Clinical Pharmacology, EarlyView.
Background Long‐acting intramuscular cabotegravir plus rilpivirine (LA‐CAB + RPV) is an effective maintenance antiretroviral regimen for virologically suppressed people with HIV. However, its use in individuals receiving chronic anticoagulation is limited by concerns regarding intramuscular bleeding risk, and real‐world data are scarce.
Montserrat Laguno, Berta Torres, Maria Martínez‐Rebollar, Paula Arreba, Octavi Roman, Roger LLobet, Leire Berrocal, Alberto Foncillas, Júlia Calvo, Abiu Sempere, Ivan Chivite, Elisa de Lazzari, Josep Mallolas, Ana González‐Cordón   +13 more
wiley   +1 more source

Identification and treatment of GOLD stages I and II chronic obstructive pulmonary disease. [PDF]

J Thorac Dis
Guan WJ, Chalmers JD, Sun YC, Agusti A, Ran PX, Halpin D, Li SY, Criner G, Zhou YM, Usmani O, Chen RC, Anzueto A, Wen FQ, Vogelmeire C, Salvi S, Zheng JP, Zhong NS.   +16 more
europepmc   +1 more source

Twenty years of inhaler therapy: A nationwide drug utilization study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to map nationwide trends and prescribing patterns in inhaler use from 2004 to 2023. In light of evolving clinical guidelines and attention to the environmental impact of inhalers within recent years, we also examined variation in prescribing behaviour and patient‐level treatment choices. Methods Using nationwide health registries,
Katrine Bitsch Johansen, Lars Christian Lund, Zandra Nymand Ennis, Andrew Scourfield, Anders Løkke, Sidsel Arnspang Pedersen   +5 more
wiley   +1 more source