Results 201 to 210 of about 407,623 (356)

Staying Offline or Going Online? Managing the Establishment of Service Platforms

open access: yesManagerial and Decision Economics, EarlyView.
ABSTRACT We study a global game in which consumers and sellers decide whether to join a service platform and interact more efficiently online. Uncertainties about the platform's technology value and users' participation behavior on both market sides cause a coordination problem.
Marit Holler   +2 more
wiley   +1 more source

Ex Vivo LRRK2 Activation in Asian G2385R and R1628P Variant Carriers and Idiopathic Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Leucine‐rich repeat kinase 2 (LRRK2) kinase inhibition is a promising therapeutic strategy for Parkinson's disease (PD), but the functional impact of Asian‐prevalent LRRK2 p.G2385R and p.R1628P variants remains unclear. Robust patient stratification and target engagement markers are needed for global LRRK2‐targeted trials ...
Tzi Shin Toh   +17 more
wiley   +1 more source

Recent Advances in the Laser‐Based Fabrication and Applications of High‐Entropy Alloy Nanoparticles

open access: yesMetalMat, EarlyView.
This review presents recent advances in the laser‐based fabrication of high‐entropy alloy nanoparticles, focusing on scalable, environmentally friendly, and compositionally tunable synthesis methods. It highlights the critical influence of laser parameters on nanoparticle size, phase, and morphology, enabling tailored properties for applications in ...
Bibek Kumar Singh   +4 more
wiley   +1 more source

Eplontersen for Hereditary Transthyretin Amyloidosis With Polyneuropathy: An Exploratory Analysis of Treatment Effect in Male and Female Patients

open access: yesMuscle &Nerve, EarlyView.
This exploratory analysis of data from the NEURO‐TTRansform trial evaluated sex‐specific responses in patients with ATTRv‐PN who had received eplontersen in NEURO‐TTRansform versus a historical placebo. Eplontersen can lead to substantial decreases in percentage serum TTR levels, arrest neuropathy impairment, and improve patient quality of life ...
Márcia Waddington Cruz   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy