Results 1 to 10 of about 5,225,150 (234)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Consumer Protection under Directive 2015/2366 on Payment Services in the Internal Market – Selected Issues

open access: yesZeszyty Naukowe Uniwersytetu Ekonomicznego w Krakowie, 2018
Directive 2007/64 on payment services (PSD 1) introduced protection for consumers of payment services. First and foremost, the consumer should receive the basic information required by law before and after the execution of a payment.
Jan Byrski
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The Relationship Between the Scope of Essential Health Benefits and Statutory Financing: An International Comparison Across Eight European Countries [PDF]

open access: yesInternational Journal of Health Policy and Management, 2016
Background Both rising healthcare costs and the global financial crisis have fueled a search for policy tools in order to avoid unsustainable future financing of essential health benefits.
Philip J. van der Wees   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

The Relationships between Costs and User Charges: The Case of a Norwegian Utility Service

open access: yesSocial Science Research Network, 2005
The paper investigates the relationships between costs and user charges in the sewage industry in Norwegian local governments. The purpose of the analysis is to answer the following questions: (i) To what extent is a higher unit cost passed on to ...
Lars-Erik Borge, J. Rattsø
semanticscholar   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Aspect-Based Sentiment Analysis on User Perceptions of OVO using Latent Dirichlet Allocation and Support Vector Machine

open access: yesAviation Electronics, Information Technology, Telecommunications, Electricals, Controls
The rapid development of digital technology and the Internet has significantly influenced financial services in Indonesia, leading to the widespread use of digital wallets.
Eka Fahira Aprilia   +2 more
doaj   +1 more source

PUBLIC ACCEPTANCE OF ROAD-USER CHARGING

open access: yesIATSS Research, 2002
This paper focuses upon public attitudes to and public acceptance of road-user charging as an effective means of managing travel demand, with the overall aim of identifying the characteristics of key interest groups, the kinds of attitudes they hold and ...
Neil THORPE
doaj   +1 more source

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