Results 91 to 100 of about 11,198 (203)

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, Volume 13, Issue 11, 23 February 2026.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Detection of feline coronavirus RNA, spike gene mutations, and feline coronavirus antigen in macrophages in aqueous humor of cats in the diagnosis of feline infectious peritonitis

Journal of Veterinary Diagnostic Investigation, 2020
Uveitis is common in cats, and is often a feature of feline infectious peritonitis (FIP). We evaluated 3 tools for detection of feline coronavirus (FCoV) in aqueous humor: 1) a 7b gene reverse-transcription real-time PCR ( 7b-RT-rtPCR) assay to detect FCoV RNA, 2) a spike gene mutation RT-rtPCR ( S-RT-rtPCR) assay to detect 2 point mutations in the ...
Laura Sangl, Sandra Felten, Kaspar Matiasek, Stefanie Dörfelt, Michele Bergmann, Hans-Jörg Balzer, Nikola Pantchev, Christian Leutenegger, Katrin Hartmann   +8 more
openaire   +3 more sources

Parameters Influencing the Plasma‐Mediated Inactivation of Microorganisms and Viruses in Wastewater

Plasma Processes and Polymers, Volume 23, Issue 2, February 2026.
Wastewater parameters, e.g., chemical oxygen demand (COD), influences the antimicrobial and antiviral efficacy of plasma. ABSTRACT Pathogenic microorganisms and viruses in water pose an environmental risk demanding for effective remediation tools like physical plasma. However, parameters influencing its efficiency are mostly descriptive.
Veronika Hahn, Ahmad Elsayed, Martina Balazinski, Robert Wagner, Michael Schmidt, Christian von Savigny, Thomas von Woedtke, Juergen F. Kolb   +7 more
wiley   +1 more source

SARS-CoV-2 in Quarantined Domestic Cats from COVID-19 Households or Close Contacts, Hong Kong, China

Emerging Infectious Diseases, 2020
We tested 50 cats from coronavirus disease households or close contacts in Hong Kong, China, for severe acute respiratory syndrome coronavirus 2 RNA in respiratory and fecal samples.
Vanessa R. Barrs, Malik Peiris, Karina W.S. Tam, Pierra Y.T. Law, Christopher J. Brackman, Esther M.W. To, Veronica Y.T. Yu, Daniel K.W. Chu, Ranawaka A.P.M. Perera, Thomas H.C. Sit   +9 more
doaj   +1 more source

Recent Advances in Lateral Flow Immunoassay for Rapid Diagnosis of Viral Diseases

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Viral diseases are a major threat to human and animal health, as illustrated by recent pandemics like COVID‐19 and African swine fever (ASF). Timely, accurate detection of viral infections is critical for effective disease control. Among diverse diagnostic techniques, lateral flow immunoassay (LFIA) has become a widely used on‐site testing tool, owing ...
Quanyu Ren, Yan Wang, Haoyuan Ma, Jialiang Xie, Jianyou Jin, Rumeng Tian, Hao Yu, Xu Gao, Nanhua Chen   +8 more
wiley   +1 more source

Serum Sialic Acid as a Biomarker of Inflammation and Infection: Insights From Veterinary Medicine

Veterinary Medicine International, Volume 2026, Issue 1, 2026.
Serum sialic acid (SSA) levels, including total sialic acid (TSA), lipid‐bound sialic acid (LBSA), and protein‐bound sialic acid (PBSA), have been extensively studied as biomarkers of inflammation and infection across various species and diseases. In parasitemic sheep, elevated SSA levels likely reflect host–pathogen interactions and immune activation.
Tina Yaghoobpour, Milad Faraji, Saeed Nazifi, Antonio Ortega-Pacheco   +3 more
wiley   +1 more source

Molecular mechanisms of severe acute respiratory syndrome (SARS)

, 2005
Severe acute respiratory syndrome (SARS) is a new infectious disease caused by a novel coronavirus that leads to deleterious pulmonary pathological features.
David A Groneberg, Groneberg, David A., Peter Zabel, Groneberg, Jan David Alexander, Zabel, Peter, Rolf Hilgenfeld, Hilgenfeld, Rolf   +6 more
core   +1 more source

Evaluation of feline mesenchymal stem cell susceptibility to feline viruses

Scientific Reports
Feline mesenchymal stem cells (fMSCs) are well known for their robust differentiation capabilities and are commonly used in studying immune-related diseases in cats.
Haoyuan Ma, Jingrui Hao, Weijian Li, Kai Yu, Kunru Zhu, Meng Yang, Shuoning Cao, Haowen Xue, Dan Liu, Yanhao Song, Siqi Zhang, Xifeng Zhang, Zheng Sun, Xu Gao   +13 more
doaj   +1 more source

Comparative in vivo analysis of recombinant type II feline coronaviruses with truncated and completed ORF3 region.

PLoS ONE, 2014
Our previous in vitro comparative study on a feline coronavirus (FCoV) pair, differing only in the intactness of their ORF3abc regions, showed that the truncated ORF3abc plays an important role in the efficient macrophage/monocyte tropism of type II ...
Ádám Bálint, Attila Farsang, Zoltán Zádori, Sándor Belák   +3 more
doaj   +1 more source

Feline Health Topics for Veterinarians, Vol. 11, No. 4, Winter/Spring 1997

, 1997
Topics in this issue include: Dr. Fred W. Scott Retires (James R. Richards); Cornell's Companion Animal Hospital Offers Radioiodine Therapy for Feline Hyperthyroidism; Task Force Recommends Vaccine Protocols; Part II: Strategies for Managing Persistent ...
Cornell Feline Health Center
core