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Mucosal Immune Response to Feline Enteric Coronavirus Infection [PDF]

Viruses, 2019
Feline infectious peritonitis is a devastating, fatal disease of domestic cats caused by a pathogenic mutant virus derived from the ubiquitous feline enteric coronavirus (FECV).
Morgan Pearson, Alora LaVoy, Samantha Evans, Allison Vilander, Craig Webb, Barbara Graham, Esther Musselman, Jonathan LeCureux, Sue VandeWoude, Gregg A. Dean   +9 more
doaj   +7 more sources

Intestinal injury and vasculitis biomarkers in cats with feline enteric coronavirus and effusive feline infectious peritonitis [PDF]

Veterinary Medicine and Science, 2023
Objective To investigate intestinal injury, repair and vasculitis biomarkers that may illuminate the progression and/or pathogenesis of feline infectious peritonitis (FIP) or feline enteric coronavirus (FECV) infection.
Erdem Gülersoy, Mahmut Ok, Kamil Üney, Murat Kaan Durgut, Tuğba Melike Parlak, Yusuf Emre Ekici   +5 more
doaj   +6 more sources

Phylogenetic analysis of feline infectious peritonitis virus, feline enteric coronavirus, and severe acute respiratory syndrome coronavirus 2 of cats in Surabaya, Indonesia [PDF]

Veterinary World, 2023
Background and Aim: Questions about the origin of coronavirus and its introduction to human beings have persisted. The detection of a variety of coronavirus related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in bats and pangolins led
Eduardus Bimo Aksono, Kania Rifa Iradatya, Teguh Hari Sucipto, Nur Syamsiatul Fajar, Wiwik Misaco Yuniarti   +4 more
doaj   +5 more sources

Candidate Gene Markers Associated with Fecal Shedding of the Feline Enteric Coronavirus (FECV) [PDF]

Pathogens, 2020
The Feline coronavirus (FCoV) can cause a fatal disease, the Feline Infectious Peritonitis. Persistent shedders represent the most important source of infection. The role of the host in FCoV fecal shedding is unknown.
Jana Bubenikova, Jana Vrabelova, Karla Stejskalova, Jan Futas, Martin Plasil, Petra Cerna, Jan Oppelt, Dana Lobova, Dobromila Molinkova, Petr Horin   +9 more
doaj   +7 more sources

Surface Display of Peptides Corresponding to the Heptad Repeat 2 Domain of the Feline Enteric Coronavirus Spike Protein on Bacillus subtilis Spores Elicits Protective Immune Responses Against Homologous Infection in a Feline Aminopeptidase-N-Transduced Mouse Model [PDF]

Frontiers in Immunology, 2022
Although feline coronavirus (FCoV) infection is extremely common in cats, there are currently few effective treatments. A peptide derived from the heptad repeat 2 (HR2) domain of the coronavirus (CoV) spike protein has shown effective for inhibition of ...
Chu Chen, Chu Chen, Ya-Li Li, Fang-Li Lv, Ling-Dong Xu, Yao-Wei Huang, Yao-Wei Huang   +6 more
doaj   +6 more sources

Structural Analysis of Inhibitor Binding to the Feline Enteric Coronavirus (FECV) Main Protease [PDF]

Viruses
Coronaviruses include various strains that reside in natural animal reservoirs, with zoonotic transmission posing risks to both domesticated animals and human health.
Arooma Maryam, Stephanie A. Moquin, Dustin Dovala, Jagroop Kaur, Nese Kurt Yilmaz, Ala M. Shaqra, Celia A. Schiffer   +6 more
doaj   +5 more sources

Antibody-dependent enhancement of serotype II feline enteric coronavirus infection in primary feline monocytes. [PDF]

Arch Virol, 2017
Feline coronavirus (FCoV) has been classified into two biotypes: avirulent feline coronavirus (feline enteric coronavirus: FECV) and virulent feline coronavirus (feline infectious peritonitis virus: FIPV). In FIPV infection, antibody-dependent enhancement (ADE) has been reported and was shown to be associated with severe clinical disease.
Takano T, Nakaguchi M, Doki T, Hohdatsu T.   +3 more
europepmc   +5 more sources

Prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and feline enteric coronavirus (FECV) in shelter-housed cats in the Central Valley of California, USA. [PDF]

Vet Rec Open, 2023
Abstract Background Non‐human animals are natural hosts for the virus causing COVID‐19 (severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2]) and a diversity of species appear susceptible to infection.
Chen D, López-Pérez AM, Vernau KM, Maggs DJ, Kim S, Foley J.   +5 more
europepmc   +7 more sources

Experimental feline enteric coronavirus infection reveals an aberrant infection pattern and shedding of mutants with impaired infectivity in enterocyte cultures. [PDF]

Sci Rep, 2016
AbstractFeline infectious peritonitis (FIP) results from mutations in the viral genome during a common feline enteric coronavirus (FECV) infection. Since many virological and immunological data on FECV infections are lacking, the present study investigated these missing links during experimental infection of three SPF cats with FECV strain UCD.
Desmarets LM, Vermeulen BL, Theuns S, Conceição-Neto N, Zeller M, Roukaerts ID, Acar DD, Olyslaegers DA, Van Ranst M, Matthijnssens J, Nauwynck HJ.   +10 more
europepmc   +6 more sources

Prevalence and mutation analysis of the spike protein in feline enteric coronavirus and feline infectious peritonitis detected in household and shelter cats in western Canada. [PDF]

Can J Vet Res, 2020
Feline infectious peritonitis (FIP) is a fatal disease for which no simple antemortem diagnostic assay is available. A new polymerase chain reaction (PCR) test has recently been developed that targets the spike protein region of the FIP virus (FIPV) and can identify specific mutations (M1030L or S1032A), the presence of which indicates a shift from ...
McKay LA, Meachem M, Snead E, Brannen T, Mutlow N, Ruelle L, Davies JL, van der Meer F.   +7 more
europepmc   +4 more sources