Results 41 to 50 of about 4,383 (171)

Crystallization of Feline Coronavirus Mpro With GC376 Reveals Mechanism of Inhibition

Frontiers in Chemistry, 2022
Coronaviruses infect a variety of hosts in the animal kingdom, and while each virus is taxonomically different, they all infect their host via the same mechanism.
Jimmy Lu, Jimmy Lu, Sizhu Amelia Chen, Sizhu Amelia Chen, Muhammad Bashir Khan, Raelynn Brassard, Raelynn Brassard, Elena Arutyunova, Elena Arutyunova, Tess Lamer, Wayne Vuong, Conrad Fischer, Howard S. Young, John C. Vederas, M. Joanne Lemieux, M. Joanne Lemieux   +15 more
doaj   +1 more source

Experimental feline enteric coronavirus infection reveals an aberrant infection pattern and shedding of mutants with impaired infectivity in enterocyte cultures. [PDF]

Sci Rep, 2016
AbstractFeline infectious peritonitis (FIP) results from mutations in the viral genome during a common feline enteric coronavirus (FECV) infection. Since many virological and immunological data on FECV infections are lacking, the present study investigated these missing links during experimental infection of three SPF cats with FECV strain UCD.
Desmarets LM, Vermeulen BL, Theuns S, Conceição-Neto N, Zeller M, Roukaerts ID, Acar DD, Olyslaegers DA, Van Ranst M, Matthijnssens J, Nauwynck HJ.   +10 more
europepmc   +5 more sources

The emerging landscape of feline coronavirus type II in Asia: A review of molecular diversity and diagnostic challenges [PDF]

BIO Web of Conferences
Feline infectious peritonitis (FIP) is a fatal systemic disease of cats caused by feline coronavirus (FCoV). FCoV is classified into two biotypes: feline enteric coronavirus (FECV) and feline infectious peritonitis virus (FIPV).
Izofani Safira, Wasissa Madarina
doaj   +1 more source

Recent Zoonotic Spillover and Tropism Shift of a Canine Coronavirus Is Associated with Relaxed Selection and Putative Loss of Function in NTD Subdomain of Spike Protein

Viruses, 2022
A canine coronavirus (CCoV) has now been reported from two independent human samples from Malaysia (respiratory, collected in 2017–2018; CCoV-HuPn-2018) and Haiti (urine, collected in 2017); these two viruses were nearly genetically identical.
Jordan D. Zehr, Sergei L. Kosakovsky Pond, Darren P. Martin, Kristina Ceres, Gary R. Whittaker, Jean K. Millet, Laura B. Goodman, Michael J. Stanhope   +7 more
doaj   +1 more source

Detection and semi-quantification of antibody to feline coronavirus in cats from the microregion of Ilhéus-Itabuna, Bahia, Brazil

Semina: Ciências Agrárias, 2021
Feline coronavirus (FCoV) is an important virus that can be differentiated into two serotypes: feline enteric coronavirus (FECoV) and feline infectious peritonitis (FIP) virus (FIPV).
Jéssica Fontes Veloso, Leonardo Sauer, Lohana Mehnati Costa e Silva, Samantha Gusmão Pellizzoni, Paula Elisa Brandão Guedes, Renata Santiago Alberto Carlos   +5 more
doaj   +1 more source

Differential in vitro inhibition of feline enteric coronavirus and feline infectious peritonitis virus by actinomycin D

Journal of General Virology, 1992
The growth of feline enteric coronavirus strain 79-1683 in whole feline embryo cells was inhibited by the presence of 1 microgram/ml of actinomycin D in the culture fluid. No virus-specific mRNAs could be detected in such cultures and yields of infectious virus were depressed by > 99%.
E L, Lewis, D A, Harbour, J E, Beringer, J, Grinsted   +3 more
openaire   +2 more sources

Molecular and pathological identification of feline coronavirus type I [PDF]

, 2012
The coronavirus in cats has been described as feline infectious peritonitis (FIPV) and feline enteric coronavirus (FECV). FIPV is highly fatal and caused immune-mediated pyogranulomatous disease, whereas FECV causes mild enteric infection. In this study,
Ajwad, Assumaidaee, Tengku Ibrahim, Tengku Azmi, Omar, Abdul Rahman, Bejo, Mohd Hair, Bande, Faruku, Arshad, Siti Suri, Amer, Alazawy   +6 more
core   +1 more source

Feline and Canine Coronaviruses: Common Genetic and Pathobiological Features

Advances in Virology, 2011
A new human coronavirus responsible for severe acute respiratory syndrome (SARS) was identified in 2003, which raised concern about coronaviruses as agents of serious infectious disease.
Sophie Le Poder
doaj   +1 more source

Genetics and Pathogenesis of Feline Infectious Peritonitis Virus

Emerging Infectious Diseases, 2009
Feline coronavirus (FCoV) is endemic in feral cat populations and cat colonies, frequently preceding outbreaks of fatal feline infectious peritonitis (FIP).
Meredith A. Brown, Jennifer L. Troyer, Jill Pecon-Slattery, Melody E. Roelke, Stephen J. O’Brien   +4 more
doaj   +1 more source

A review of feline infectious peritonitis virus infection [PDF]

Veterinary World
Feline infectious peritonitis (FIP) is an infectious disease characterized by non-specific laboratory changes and clinical signs. Clinical symptoms include anorexia, jaundice, fever, and weight loss.
Tridiganita Intan Solikhah, Qurrotul Aini Dwi Agustin, Ratmasari Alifina Damaratri, Della Ayuke Fika Siwi, Ghulam Naufal Rafi’uttaqi, Vincent Angelino Hartadi, Gahastanira Permata Solikhah   +6 more
doaj   +1 more source