Results 41 to 50 of about 4,305 (143)

Comparative in vivo analysis of recombinant type II feline coronaviruses with truncated and completed ORF3 region.

PLoS ONE, 2014
Our previous in vitro comparative study on a feline coronavirus (FCoV) pair, differing only in the intactness of their ORF3abc regions, showed that the truncated ORF3abc plays an important role in the efficient macrophage/monocyte tropism of type II ...
Ádám Bálint, Attila Farsang, Zoltán Zádori, Sándor Belák   +3 more
doaj   +1 more source

Comparison of Clinical and Laboratory Findings at Different Clinical Stages in Cats Naturally Infected with Feline Coronavirus

Acta Veterinaria, 2023
Feline coronavirus (FCoV) infections occur commonly in cats, with entrocyte and monocyte-macrophage tropism. Most FCoV-infected cats remain asymp tomatic, but up to 10% develop fatal feline infectious peritonitis (FIP). This study aims to investigate the
Gülersoy Erdem, Ok Mahmut, Üney Kamil, Durgut Murat Kaan, Parlak Tuğba Melike, Ekici Yusuf Emre   +5 more
doaj   +1 more source

Experimental feline enteric coronavirus infection reveals an aberrant infection pattern and shedding of mutants with impaired infectivity in enterocyte cultures. [PDF]

Sci Rep, 2016
AbstractFeline infectious peritonitis (FIP) results from mutations in the viral genome during a common feline enteric coronavirus (FECV) infection. Since many virological and immunological data on FECV infections are lacking, the present study investigated these missing links during experimental infection of three SPF cats with FECV strain UCD.
Desmarets LM, Vermeulen BL, Theuns S, Conceição-Neto N, Zeller M, Roukaerts ID, Acar DD, Olyslaegers DA, Van Ranst M, Matthijnssens J, Nauwynck HJ.   +10 more
europepmc   +5 more sources

Plant‐Derived Probiotics From Fermented Foods: Current Evidence on Antiviral Mechanisms and Gut–Lung Axis Modulation

Food Frontiers, Volume 7, Issue 6, November 2026.
Plant‐derived probiotics from fermented foods exert anti‐respiratory virus effects via immune regulation, antiviral metabolites, and gut–lung axis, highlighting their advantages, key technologies, and application prospects. ABSTRACT Respiratory viral infections represent a major global public health threat, causing widespread morbidity, mortality, and ...
Yinghao Xing, Yaoyuan Hu, Yingying Ma, Peng Yao, Jingjing Jiang, Jiao Guo, Shuangmei Liu   +6 more
wiley   +1 more source

A colloidal gold immunochromatographic test strip based on mAbs anti-N protein to detect feline coronavirus

Microbiology Spectrum
Feline coronavirus (FCoV) includes Feline enteric coronavirus (FECV) and feline infectious peritonitis virus (FIPV). FECV primarily affects the gastrointestinal system of cats, causing mild and self-limiting gastrointestinal symptoms.
Zhe Liu, Yupeng Yang, Ruibin Qi, Haorong Gu, Mengru Chen, Kexin Feng, Qian Jiang, Honglin Jia, Hongtao Kang, Jiasen Liu   +9 more
doaj   +1 more source

Diagnosis of Feline Infectious Peritonitis: A Review of the Current Literature

Viruses, 2019
Feline infectious peritonitis (FIP) is a fatal disease that poses several challenges for veterinarians: clinical signs and laboratory changes are non-specific, and there are two pathotypes of the etiologic agent feline coronavirus (FCoV), sometimes ...
Sandra Felten, Katrin Hartmann
doaj   +1 more source

Antigenic Activity of Canine Enteric Coronavirus Strain "Rich" in Experiments with Rabbits, Ferrets and Guinea Pigs

Ветеринарная патология, 2023
Introduction. Canine enteric coronavirus is a widespread infection, especially dangerous for the puppies of up to 12 weeks old kept in shelters and breeding kennels. The causative agent Alphacoronavirus 1 has a high mutational variability.
A. A. Komarova, T. S. Galkina
doaj   +1 more source

Integrative in silico and in vitro screening of small molecules targeting RNA

Current Protocols, Volume 6, Issue 8, August 2026.
Abstract Targeting structured RNA elements with small molecules has emerged as a promising yet technically challenging strategy for antiviral drug discovery. Here, we present a comprehensive and experimentally validated workflow for the integrative in silico and in vitro screening of RNA‐binding small molecules.
Sabrina Toews, Megan Ken, Harald Schwalbe   +2 more
wiley   +1 more source

A Retrospective Study of Viral Molecular Prevalences in Cats in Southern Italy (Campania Region)

Viruses, 2022
From 2019 to 2021, a retrospective molecular study was conducted in the Campania region (southern Italy) to determine the prevalence of viral diseases in domestic cats. A total of 328 dead animals were analyzed by Real-Time PCR for the presence of feline
Maria Grazia Amoroso, Francesco Serra, Gianluca Miletti, Lorena Cardillo, Claudio de Martinis, Luisa Marati, Flora Alfano, Gianmarco Ferrara, Ugo Pagnini, Esterina De Carlo, Giovanna Fusco, Serena Montagnaro   +11 more
doaj   +1 more source

Prevalence and mutation analysis of the spike protein in feline enteric coronavirus and feline infectious peritonitis detected in household and shelter cats in western Canada. [PDF]

Can J Vet Res, 2020
Feline infectious peritonitis (FIP) is a fatal disease for which no simple antemortem diagnostic assay is available. A new polymerase chain reaction (PCR) test has recently been developed that targets the spike protein region of the FIP virus (FIPV) and can identify specific mutations (M1030L or S1032A), the presence of which indicates a shift from ...
McKay LA, Meachem M, Snead E, Brannen T, Mutlow N, Ruelle L, Davies JL, van der Meer F.   +7 more
europepmc   +2 more sources