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Vaccination against feline leukaemia using a new feline herpesvirus type 1 vector

Vaccine, 1996
A recombinant feline herpesvirus type 1 (FHV-1) was constructed expressing the envelope glycoprotein gene from feline leukaemia virus (FeLV). The expression cassette containing the long terminal repeat promoter from Rous sarcoma virus was stably integrated at the locus downstream of the gC homologue in FHV-1. Oronasal vaccination with recombinant FHV-1
M J, Willemse   +3 more
openaire   +2 more sources

Culture of feline corneal epithelial cells and infection with feline herpesvirus-1 as an investigative tool

American Journal of Veterinary Research, 2005
Abstract Objective—To isolate and characterize pure cultures of feline corneal epithelial cells and to assess the extent and nature of feline herpesvirus (FHV)-1 infection in these cells. Sample Population—Healthy eyes from 23 recently euthanatized cats.
Lynne S, Sandmeyer   +2 more
openaire   +2 more sources

Activation of feline immunodeficiency virus long terminal repeat by feline herpesvirus type 1

Virology, 1991
By transfection of a recombinant plasmid containing the feline immunodeficiency virus (FIV) long terminal repeat (LTR) linked to the chloramphenicol acetyltransferase (CAT) gene followed by infection of feline herpesvirus type 1 (FHV-1) into Crandell feline kidney cells and Felis catus whole fetus 4 cells, enhancement of CAT activity was demonstrated ...
Y, Kawaguchi   +6 more
openaire   +2 more sources

Heparin-binding activity of feline herpesvirus type 1 glycoproteins

Virus Research, 1997
Feline herpesvirus type 1 (FHV-1) possesses a very narrow host range, but the mechanism of its infection has not yet been analyzed. Heparan sulfate on the cell surface serves as a receptor for several herpesviruses. In this study, we determined that infection of FHV-1 is inhibited by addition of soluble heparin in cells cultures. Using heparin-affinity
K, Maeda   +4 more
openaire   +2 more sources

Genetic Rearrangements in the gC Gene of the Feline Herpesvirus Type 1

Virus Genes, 2004
In the field isolate, 91-58, of feline herpesvirus type 1 (FHV-1), one of the major immunogenic proteins was found to have different molecular masses of 75 and 130 kDa from those in the other field isolates (Maeda et al., J Vet Med Sci 57, 147-150, 1995).
Masataka, Hamano   +6 more
openaire   +2 more sources

Restriction endonuclease mapping of the genome of feline herpesvirus type 1

Archives of Virology, 1991
Restriction endonuclease mapping was used to determine the molecular structure of feline herpesvirus type 1 (FHV-1) strain B 927. FHV-1 DNA purified from infected cells by pulsed field gel electrophoresis was partially restricted with Sau 3A to generate a series of overlapping fragments of 10-20 kb.
A, Grail, D A, Harbour, W, Chia
openaire   +2 more sources

Use of serologic tests to predict resistance to feline herpesvirus 1, feline calicivirus, and feline parvovirus infection in cats

Journal of the American Veterinary Medical Association, 2002
Abstract Objective—To determine whether detection of virusspecific serum antibodies correlates with resistance to challenge with virulent feline herpesvirus 1 (FHV-1), feline calicivirus (FCV), and feline parvovirus (FPV) in cats and to determine percentages of client-owned cats with serum antibodies to FHV-1, FCV, and FPV.
Michael R, Lappin   +3 more
openaire   +2 more sources

Clinical refresher Feline herpesvirus - 1 keratitis

Companion Animal, 2007
Recrudescent infection An estimated 80% of these infected animals become latently affected, with the virus present in the trigeminal ganglion life-long. All signs may resolve and the cat may remain asymptomatic for life. However in approximately half of these latently affected cats, the virus may become reactivated later in life. In many of these cases,
openaire   +1 more source

Substrate specificity and molecular modelling of the feline herpesvirus-1 thymidine kinase

Archives of Virology, 2007
Feline herpesvirus-1 (FHV-1) causes a severe upper respiratory and ocular disease in cats. An effective antiviral compound is required for treating FHV-1 infections. The virus-encoded thymidine kinase (TK) is the molecular basis for selective activation of commonly used antiviral nucleoside analogue drugs, e.g.
Islam T M, Hussein   +3 more
openaire   +2 more sources

Identification and Characterization of the Feline Herpesvirus Type 1 Glycoprotein C Gene

Virus Genes, 1997
The feline herpesvirus type 1 (FHV-1) gene encoding glycoprotein C (gC) has been sequenced and identified based on its genomic location and comparative analysis to other alphaherpesvirus gCs, and the expressed gC protein was also identified by using specific monoclonal antibodies.
K, Maeda   +3 more
openaire   +2 more sources

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