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Melanoma Cells Exposed to Clomiphene Citrate Respond With Cell Cycle Arrest and Reduced Invasiveness

Journal of Applied Toxicology, EarlyView.
ABSTRACT Epidemiological studies have suggested that clomiphene citrate (CC) exposure may increase the risk of malignant melanoma, but mechanisms are unknown. We investigated the effects of CC on melanoma cell line A375. Cells were treated with CC at 2, 20, 200, and 2000 ng/mL, followed by assessment of cell viability and metabolism, cell cycle ...
Thaís S. Ribeiro +8 more
wiley +1 more source

Accessory Cavitated Uterine Malformation (ACUM): A Case Series

Journal of Clinical Ultrasound, EarlyView.
Accessory cavitated uterine malformation (ACUM) can be misdiagnosed as other uterine pathologies, such as mullerian anomalies, adenomyosis or fibroids. Imaging, particularly gynecological ultrasound plays a fundamental role in identifying this condition.
Luis Felipe Aravena +8 more
wiley +1 more source

De Felipe IV a Felipe V. La disolución de algunas jurisdicciones señoriales en Castilla la Vieja

Investigaciones Históricas. Época Moderna y Contemporánea, 2022
Castilla la Vieja se caracteriza por una especial complejidad jurisdiccional. Entre las jurisdicciones castellanas figuran algunas que ejercían villas importantes y que se extendían a decenas de lugares y villas con jurisdicción parcial, caso de las de Briviesca, Villadiego, Frías, Cerezo de Río Tirón y Belorado, todas de señorío de los duques de Frías.
openaire +2 more sources

Critical Appraisal of Pancreaticogastrostomy After Pancreatoduodenectomy: Evolution, Evidence, and Future Prospects

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Pancreaticogastrostomy (PG) emerged as a reconstructive option after pancreaticoduodenectomy (PD) due to its reported lower incidence of postoperative pancreatic fistula (POPF), but its superiority over pancreaticojejunostomy (PJ) remains unclear.
Samuel Menezes +4 more
wiley +1 more source

Estimating Soil Compaction Risk at Regional Scales Using Meteorological Data and Soil Spectroscopy

Land Degradation &Development, EarlyView.
ABSTRACT Soil compaction is a significant form of soil degradation in Europe, reducing agricultural productivity, limiting carbon sequestration and increasing greenhouse gases emissions. In response, the forthcoming European Union Soil Monitoring and Resilience Law requires spatial assessment of topsoil and subsoil compaction risk at district, that is,
Felipe Bachion de Santana +7 more
wiley +1 more source

El carácter voluntario de los donativos indianos, entre la praxis institucional y la construcción del consenso (siglos XVI-XVII)

Historia Mexicana El Colegio de México, 2018
Al leer las principales investigaciones relativas a los donativos voluntarios, solicitados por los Habsburgo de España a lo largo del siglo XVII, es posible llegar a dos conclusiones principales. Primera: la petición del donativo, si bien tuvo lugar a lo
Loris De Nardi
doaj +1 more source

Las armadas de Felipe IV. La conservación de la Monarquía

Revista Historia Autónoma, 2018
After an overview of books, articles and presentations of recent decades in naval historiography, we can observe how the situation of naval power during the reign of Philip IV was analysed from different historiographic perspectives, and how all of them offer us an incomplete knowledge today. This article seeks to understand the sea as an area of union
openaire +3 more sources

Genome‐Wide Assessment Reveals Ancestral Differences in Homozygosity Patterns Potentially Linked to Parkinson's Disease Etiology

Movement Disorders, EarlyView.
Abstract Background Recessive genetic variation and extended runs of homozygosity (ROHs) may contribute to the unexplained heritability of Parkinson's disease (PD), particularly in diverse and understudied populations. Objective We conducted the first large‐scale, multi‐ancestral investigation of PD to examine the impact of genome‐wide homozygosity on ...
Kathryn Step +680 more
wiley +1 more source

Cédula de Felipe IV sobre el derecho a la media anata [PDF]

Trocadero, 2010
En este artículo realizamos el estudio de un documento generado, a partir de una Cédula emitida por Felipe IV, con la finalidad de hacer efectivo en Cádiz el cobro de un impuesto, el de la media anata.
openaire +2 more sources

Floral resource diversity drives spatiotemporal variation in plant–pollinator network structure

Oikos, EarlyView.
Mechanisms underlying community assembly, including those related to species interactions, vary across space and time. Plant–pollinator networks exemplify these dynamics, where link rewiring and turnover mediate adaptations to environmental changes. Bees rely on diverse floral resources (e.g.
Caio S. Ballarin +3 more
wiley +1 more source

history general and history of europe
política
siglo xvii

history of the arts
españa
mito

literatura
modern history, 1453-
fotografías-españa-s. xx