Results 1 to 10 of about 216,996 (340)
Mitochondrial Oxidative Stress and “Mito-Inflammation”: Actors in the Diseases
Biomedicines, 2021 A decline in mitochondrial redox homeostasis has been associated with the development of a wide range of inflammatory-related diseases. Continue discoveries demonstrate that mitochondria are pivotal elements to trigger inflammation and stimulate innate ...
Alessandro Rimessi +2 more
exaly +2 more sources
Mitochondrial Recombination Reveals Mito–Mito Epistasis in Yeast [PDF]
Genetics, 2018 Abstract Genetic variation in mitochondrial DNA (mtDNA) provides adaptive potential although the underlying genetic architecture of fitness components within mtDNAs is not known. To dissect functional variation within mtDNAs, we first identified naturally occurring mtDNAs that conferred high or low fitness in Saccharomyces cerevisiae by ...
Guillaume Charron +2 more
exaly +3 more sources
Molecular Therapy - Nucleic Acids, 2020 Here, we report on validating a mitochondrial gene therapy by delivering nucleic acids to mitochondria of diseased cells by a MITO-Porter, a liposome-based carrier for mitochondrial delivery.
Takashi Yokota +2 more
exaly +2 more sources
Endocrinology, Diabetes & Metabolism Case Reports, 2023 Unawareness of postprandial hypoglycemia for 5 years was identified in a 66-year-old man at a local clinic. The patient was referred to our hospital because of this first awareness of hypoglycemia (i.e.
Rikako Nakajima +11 more
doaj +1 more source
Journal of Diabetes Investigation, 2022 Aims/Introduction The importance of low‐density lipoprotein cholesterol (LDL‐C) in the primary prevention of cardiovascular disease has recently been reported in the population aged ≥75 years with hypercholesterolemia.
Yuki Yamamoto +6 more
doaj +1 more source
Cancer stem cell fate determination: mito-nuclear communication
Cell Communication and Signaling, 2023 Cancer stem cells (CSCs) are considered to be responsible for tumor recurrence and metastasis. Therefore, clarification of the mechanisms involved in CSC stemness maintenance and cell fate determination would provide a new strategy for cancer therapy ...
M. Fan, Ying Shi, Ju-Mei Zhao, Ling Li
semanticscholar +1 more source
Spontaneous retroperitoneal bleeding secondary to celiac artery compression syndrome
Clinical Case Reports, 2021 Clinicians should consider celiac artery compression syndrome as the cause of ruptured visceral aneurysm and dissection and ask patients for unexplained chronic abdominal symptoms.
Kazuya Nagasaki +4 more
doaj +1 more source
Scientific Reports, 2023 Whole mitochondrial genomes are often used in phylogenetic reconstruction. However, discordant patterns in species relationships between mitochondrial and nuclear phylogenies are commonly observed.
A. Quattrini +9 more
semanticscholar +1 more source
Acta Medica, 2020 Lung metastasis and metachronous double primary lung cancer are both common and often present diagnostic challenges. We present a case of metachronous isolated contralateral lung metastasis from pulmonary adenosquamous carcinoma with EGFR mutation.
Hitomi Kawai +4 more
doaj +1 more source
Bone Healing in Adolescents with Bilateral L5 Spondylolysis with and without Preexisting Contralateral Terminal Spondylolysis [PDF]
Asian Spine Journal, 2021 Study Design Retrospective cohort study Purpose To examine bone healing with conservative treatment in cases of adolescent bilateral L5 spondylolysis.
Fumihiko Eto +5 more
doaj +1 more source