Results 31 to 40 of about 618,328 (350)

Mesentero-axial gastric volvulus treated with laparoscopic gastropexy: a case report

Surgical Case Reports, 2023
Background Mesentero-axial gastric volvulus (MAGV) is an uncommon subtype of gastric volvulus (GV). However, reports of such cases in adult patients are very rare. We present an unusual case of idiopathic MAGV in an old woman.
Masato Kawahara, Tsunehiko Maruyama, Yoshiki Kaneko, Naoaki Konno, Hiroshi Kashimura, Tatsuya Oda   +5 more
doaj   +1 more source

Mitofusins and OPA1 Mediate Sequential Steps in Mitochondrial Membrane Fusion [PDF]

, 2009
Mitochondrial fusion requires the coordinated fusion of the outer and inner membranes. Three large GTPases—OPA1 and the mitofusins Mfn1 and Mfn2—are essential for the fusion of mammalian mitochondria.
David C. Chan, J. Michael Mccaffery, Janet M. Shaw, Mariam Ghochani, Terrence G. Frey, Zhiyin Song   +5 more
core   +2 more sources

Insulinoma presenting with anti-insulin antibodies

Endocrinology, Diabetes & Metabolism Case Reports
An 89-year-old woman presented with a 6-year history of occasional episodes of impaired consciousness that were relieved by ingestion of a snack. Three months before presenting to our hospital, she had been hospitalized in a local hospital with subdural ...
Rikako Nakajima, Daisuke Sato, Ichirota Togashi, Hiroto Idesawa, Jun Ito, Kei Ito, Masanao Fujii, Hiroaki Yagyu   +7 more
doaj   +1 more source

Comparison of glucose monitoring between Freestyle Libre Pro and iPro2 in patients with diabetes mellitus

Journal of Diabetes Investigation, 2019
Aims/Introduction Flash and continuous glucose monitoring systems are becoming prevalent in clinical practice. We directly compared a flash glucose monitoring system (FreeStyle Libre Pro [FSL‐Pro]) with a continuous glucose monitoring system (iPro2) in ...
Ryo Kumagai, Aiko Muramatsu, Masanao Fujii, Yukino Katakura, Kei Ito, Keiko Fujie, Yoshio Nakata, Koichi Hashimoto, Hiroaki Yagyu   +8 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Generation of trans-mitochondrial mito-mice by the introduction of a pathogenic G13997A mtDNA from highly metastatic lung carcinoma cells [PDF]

, 2010
To investigate the effects of respiration defects on the disease phenotypes, we generated trans-mitochondrial mice (mito-mice) by introducing a mutated G13997A mtDNA, which specifically induces respiratory complex I defects and metastatic potentials in ...
Hashizume Osamu, Hayashi Jun-Ichi, Ishii Rie, Ishikawa Kaori, Nakada Kazuto, Shitara Hiroshi, Takenaga Keizo, Taya Choji, Yokota Mutsumi, Yonekawa Hiromichi, 林 純一, 横田 睦美   +11 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Delayed traumatic intracerebral hematoma presenting as cortical deafness: case report

Heliyon, 2020
Cortical deafness is a rare condition and is usually caused by bilateral cerebral lesions. Several cases of sudden cortical deafness caused by ischemic stroke or hypertensive intracerebral hematoma have been reported, however, no cases of traumatic ...
Yasushi Shibata
doaj   +1 more source

Mito & contracultura

Mediações - Revista de Ciências Sociais, 2007
Considerada irracional desde os seus primórdios, a crítica à contracultura revelou-se incapaz de perceber a revolução cognitiva que se instaurava com as diferentes práticas de espiritualidade. Substituindo a lógica racionalista da exclusão pela lógica da inclusão, onde os elementos se equivalem, o movimento contracultural resgatou a experiência mítica,
openaire   +4 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source