Results 51 to 60 of about 618,328 (350)

Bioinspired, Mitochondria‐Targeted Single‐Atom Nanozyme Enhances Bone Regeneration by Reprogramming Stem Cell Energy Metabolism​

Advanced Materials, EarlyView.
A bioinspired nanozyme—triphenylphosphonium (TPP)‐dendritic mesoporous silica nanoparticle (DMSN)‐Fe/Cu—mimics mitochondrial complex IV and targets mitochondria to regulate cellular energy metabolism. This approach markedly boosts bone regeneration in vivo, as demonstrated by enhanced bone volume and mineral density in critical‐sized bone defects rat ...
Yuwen Wang, Xinzhi Liang, Tiandi Xiong, Zheng Zhong, Ning Zhang, Boguang Yang, Dong Li, Qiongjiao Zeng, Xian Chen, Yiting Lei, Shangsi Chen, Chao Zheng, Liu Yang, Wei Huang, Rocky S. Tuan, Denghui Xie, Zhong Alan Li   +16 more
wiley   +1 more source

Intracerebral Hemorrhage During the Chronic Phase of Eosinophilic Granulomatosis With Polyangiitis: A Case Report Emphasizing Cerebrovascular Vulnerability

Clinical Case Reports
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare form of small‐vessel vasculitis typically associated with eosinophilia, asthma, and systemic inflammation.
Shinya Watanabe, Masatoshi Kasuya, Yasushi Shibata   +2 more
doaj   +1 more source

A myth in time: Victor Erice's El sur [PDF]

, 1996
En este artículo se estudia tiempo e identidad, mitos y cine en El sur de Victor Erice. Basándose en un análisis de dos escenas, se plantea una relación entre eléxito o fracaso personal, la capacidad para construir mitos, y el transcurso del tiempo.
Evans, J
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ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Idiopathic Normal-Pressure Hydrocephalus Revealed by Systemic Infection: Clinical Observations of Two Cases

Neurology International
Background/Objectives: Idiopathic normal-pressure hydrocephalus (iNPH) is a potentially reversible neurological disorder characterized by gait disturbance, cognitive impairment, and urinary incontinence.
Shinya Watanabe, Yasushi Shibata, Kosuke Baba, Yuhei Kuriyama, Eiichi Ishikawa   +4 more
doaj   +1 more source

Papel psicológico del mito [PDF]

, 1973
Tesina para la obtención de Licenciatura en Filosofía y Letras (Sección: Psicología). Universidad de Barcelona. Dirigida por el Dr. Alejandro Sanvisens.
Castro Esteban, Ana Delia
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Microglia Mitochondria Support Neuronal Maturation via Metabolic and Transcriptional Reprogramming in Human 3D In Vitro Brain Model

Advanced Science, EarlyView.
xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben, Charitha C. Anamala, Sahan B. S. Kansakar, Vaishnavi Koduri, Volha Liaudanskaya   +4 more
wiley   +1 more source

Biogenesis of mitochondrial porin [PDF]

, 1990
We review here the present knowledge about the pathway of import and assembly of porin into mitochondria and compare it to those of other mitochondrial proteins.
A. Grossmann, A. L. Horwich, B. L. Geller, B. Schmidt, C. Smagula, C. Witte, C. Zwizinski, C. Zwizinski, D. M. Kolansky, D. Roise, D. Vestweber, D. W. Nicholson, E. C. Hurt, E. C. Hurt, E. C. Hurt, E. C. Hurt, F.-U. Hartl, G. Hallermayer, G. Hawlitschek, G. Heijne von, G. S. Adrian, H. Aquila, H. Aquila, H. Freitag, H. Freitag, H. Freitag, H. Murakami, H. Ono, H. Wiech, J. A. Rothblatt, K. Mihara, K. Mihara, L. Chen, M. Colombini, M. Eilers, M. Eilers, M. G. Waters, M. Linden, M. Mueckler, M. P. Yaffe, M. Schleyer, M. Schleyer, M. Schwaiger, M. Y. Cheng, M. Yang, N. Pfanner, N. Pfanner, N. Pfanner, N. Pfanner, N. Pfanner, N. Pfanner, N. Pflanner, R. A. Pollock, R. A. Stuart, R. Benz, R. E. Jensen, R. J. Deshaies, R. Jaenicke, R. Kleene, R. Kleene, R. Pfaller, R. Pfaller, R. Pfaller, R. Pfaller, R. Zimmermann, S. Hamajima, S. M. Gasser, S. M. Gasser, T. Hase, T. Imanaka, U. I. Flügge, W. Hansen, W. J. Chirico, W. Neupert, W.-J. Chen   +74 more
core   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Sintesi di analoghi tiomorfolonici di benzopirani 4-spiro sostituiti ad attività antischemica [PDF]

, 2009
I canali al potassio ATP-sensibili mitocondriali (mito-KATP)sono coinvolti in un meccanismo cardioprotettivo detto precondizionamento ischemico (IPC).Molecole capaci di attivare i canali mito-KATP, mimando il fenomeno dell'IPC, possono risultare utili ...
BASILE, MARIA
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