Results 41 to 50 of about 11,973,388 (377)

Signaling pathways linking behavior to neurogenesis in healthy brain and disease [PDF]

, 2020
Self-repair of the adult brain is limited – most diseases lack effective therapy. In order to better understand how a regenerative response can be achieved, studying mechanisms shaping the neurogenic niche, from environmental factors to intrinsic ...
Klempin, Friederike
core   +1 more source

Geographic variation in walking activity in the red flour beetle Tribolium castaneum

Population Ecology, EarlyView.
This study examined whether there is geographic variation in field populations, focusing on the moving activity in the red flour beetle Tribolium castaneum. Results showed significant differences in moving activity among field populations but no correlation with latitude or meteorological factors.
Kentarou Matsumura
wiley   +1 more source

Pregnancy Outcomes After Higher-Order Multifetal Pregnancy Reduction: A Retrospective Study

International Journal of Clinical Practice
Conclusion: Prevention is the most important measure to decrease the incidence of multiple pregnancies. For higher-order multifetal pregnancies, multifetal pregnancy reduction (MFPR) is considered a significant remedial measure.
Mengjie Fan, Li Li, Yanyi Li, Liying Wang, Hongxia Zhang, Shuo Yang, Jia Li, Ying Song, Di Sun, Danlei Zheng, Tian Tian, Caihong Ma, Ping Liu, Jie Qiao, Rui Yang, Rong Li   +15 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Measuring Urinary Sensation with Current Perception Threshold: A Comparison between Method of Limits and Method of Levels

Obstetrics and Gynecology International, 2012
Purpose. To determine the association between the two methods of obtaining current perception thresholds (CPTs) in the lower urinary tract (LUT). Materials and Methods.
Carley Davis, Lior Lowenstein, Elizabeth Mueller, Linda Brubaker, Kimberly Kenton   +4 more
doaj   +1 more source

Patient-reported goal achievements after pelvic floor muscle training versus pessary in women with pelvic organ prolapse. A randomised controlled trial

Journal of Obstetrics and Gynaecology, 2023
The aim was to assess the achievement by self-determined goals in pelvic organ prolapse (POP) participants receiving pelvic floor muscle training (PFMT) compared to vaginal pessary.
Wongsakorn Limbutara, Suvit Bunyavejchevin, Purim Ruanphoo, Keerati Chiengthong   +3 more
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Retained Fetal Bone in Infertile Patients: Two Case Reports [PDF]

International Journal of Fertility and Sterility, 2009
The prolonged retention of fetal bone structure is an uncommon condition after a previous abortion. We describe two cases with fetal bone fragment amongst 3589 hysteroscopies (0.05%) who had no complaint other than secondary infertility. In both patients
Firoozeh Ghaffari, Ensieh ShahrokhTehraninejad, Kiandokht Kiani   +2 more
doaj   +1 more source

Transcriptional and translational differences of microglia from male and female brains [PDF]

, 2019
Sex differences in brain structure and function are of substantial scientific interest because of sex-related susceptibility to psychiatric and neurological disorders. Neuroinflammation is a common denominator of many of these diseases and thus microglia
Güneykaya, Dilansu
core   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source