Results 41 to 50 of about 8,726,539 (311)

Measuring Urinary Sensation with Current Perception Threshold: A Comparison between Method of Limits and Method of Levels

Obstetrics and Gynecology International, 2012
Purpose. To determine the association between the two methods of obtaining current perception thresholds (CPTs) in the lower urinary tract (LUT). Materials and Methods.
Carley Davis, Lior Lowenstein, Elizabeth Mueller, Linda Brubaker, Kimberly Kenton   +4 more
doaj   +1 more source

Retained Fetal Bone in Infertile Patients: Two Case Reports [PDF]

International Journal of Fertility and Sterility, 2009
The prolonged retention of fetal bone structure is an uncommon condition after a previous abortion. We describe two cases with fetal bone fragment amongst 3589 hysteroscopies (0.05%) who had no complaint other than secondary infertility. In both patients
Firoozeh Ghaffari, Ensieh ShahrokhTehraninejad, Kiandokht Kiani   +2 more
doaj   +1 more source

CXCL13 shapes immunoactive tumor microenvironment and enhances the efficacy of PD-1 checkpoint blockade in high-grade serous ovarian cancer

Journal for ImmunoTherapy of Cancer, 2021
Background Most patients with high-grade serous ovarian cancer (HGSC) lack an effective response to immune checkpoint blockade, highlighting the need for more knowledge about what is required for successful treatment. As follicular cytotoxic CXCR5+CD8+ T
Congjian Xu, Moran Yang, Jiaqi Lu, Guodong Zhang, Yiying Wang, Mengdi He, Haiou Liu   +6 more
doaj   +1 more source

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

FEBS Letters, Volume 599, Issue 7, Page 1055-1074, April 2025.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard, Bernadette R. Gochuico, Hadass Pri Chen, Christopher K. E. Bleck, Patricia M. Zerfas, Wendy J. Introne, William A. Gahl, May C. V. Malicdan   +7 more
wiley   +1 more source

Toll-like receptor 4 promotes proliferation and apoptosis resistance in human papillomavirus–related cervical cancer cells through the Toll-like receptor 4/nuclear factor-κB pathway

Tumor Biology, 2017
Toll-like receptor 4 is overexpressed in various tumors, including cervical carcinoma. However, the role of Toll-like receptor 4 in cervical cancer remains controversial, and the underlying mechanisms are largely elusive.
Ninghong Jiang, Feng Xie, Qisang Guo, Ming-Qing Li, Jingjing Xiao, Long Sui   +5 more
doaj   +1 more source

Siglec-9+ tumor-associated macrophages delineate an immunosuppressive subset with therapeutic vulnerability in patients with high-grade serous ovarian cancer

Journal for ImmunoTherapy of Cancer, 2023
Background The potent immunosuppressive properties of sialic acid-binding immunoglobulin-like lectin-9 (Siglec-9) on myeloid cells and lymphocytes provide a strong rationale for serving as a therapeutic target.
Yan Huang, Chen Zhang, Wei Jiang, Moran Yang, Guodong Zhang, Yiying Wang, Mengdi He, Haiou Liu, Kankan Cao   +8 more
doaj   +1 more source

Long-term effects of female teacher on her pupils' smoking behaviour later in life [PDF]

arXiv, 2021
In Japan, teacher and student is randomly matched in the first year of elementary school. Under the quasi-natural experimental setting, we examine how learning in female teacher homeroom class in the elementary school influence pupils' smoking behavior after they become adult. We found that pupils are unlikely to smoke later in life if they belonged to
arxiv  

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

FEBS Letters, Volume 599, Issue 7, Page 1006-1028, April 2025.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause, Musalula Sinkala, Raj Ramesar   +2 more
wiley   +1 more source

Corticosterone selectively decreases humoral immunity in female eiders during incubation [PDF]

J. Exp. Biol. 209 (2006) 4957-4965, 2007
Immunity is hypothesized to share limited resources with other physiological functions and this may partly account for the fitness costs of reproduction. Previous studies have shown that the acquired immunity of female common eider ducks (Somateria mollissima) is suppressed during their incubation, during which they entirely fast.
arxiv   +1 more source

Eleventh annual report of the New England Female Medical College [PDF]

Nègre Ernest. Les noms de lieux Combres, Combret, Combraille en France. In: Nouvelle revue d'onomastique, n°3-4, 1984. L'Auvergne. pp.
Trustees of the New-England Female Medical College
core   +1 more source