Results 41 to 50 of about 4,673,582 (318)

Exposure to high dose of polystyrene nanoplastics causes trophoblast cell apoptosis and induces miscarriage

Particle and Fibre Toxicology
Background With rapid increase in the global use of various plastics, microplastics (MPs) and nanoplastics (NPs) pollution and their adverse health effects have attracted global attention.
Shukun Wan, Xiaoqing Wang, Weina Chen, Manli Wang, Jingsong Zhao, Zhongyan Xu, Rong Wang, Chenyang Mi, Zhaodian Zheng, Huidong Zhang   +9 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Natural cycle versus modified natural cycle for endometrial preparation in women undergoing frozen-thawed embryo transfer: An RCT

International Journal of Reproductive BioMedicine, 2022
Background: Studies have evaluated different endometrial preparation methods, but the optimal frozen-thawed embryo transfer (FET) cycle strategy in terms of the in-vitro fertilization outcome is still debated.
Maryam Farid Mojtahedi, Saeedeh Aref, Ashraf Moini, Arezoo Maleki-Hajiagha, Ladan Kashani   +4 more
doaj   +1 more source

Inducible co-stimulatory molecule (ICOS) alleviates paclitaxel-induced neuropathic pain via an IL-10-mediated mechanism in female mice [PDF]

, 2023
Ishwarya Sankaranarayanan, Diana Tavares‐Ferreira, Juliet M. Mwirigi, Galo L. Mejia, Michael D. Burton, Theodore J. Price   +5 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Achieving functional remission in schizophrenia: a pilot study

European Psychiatry
Introduction Many patients with schizophrenia are unable to achieve adequate levels of psychosocial functioning and quality of life despite of the remission of illness symptoms.
D. Bošnjak Kuharić, A. Jambrošić Sakoman, Z. Lovrić Makarić, A. Savić, A. Papić, M. Herceg   +5 more
doaj   +1 more source

Successful Treatment of Obstructive Oligospermia/Azoospermia Due to Mullerian Duct Cyst by Transurethral Resection: A Case Report [PDF]

International Journal of Fertility and Sterility, 2007
Cystic lesions in midline of prostate are uncommon and considered as congenital disorders. Here we report a 33- year- old male who presented with either azoospermia or decreased ejaculate volume leading to infertility and for whom performing Transrectal ...
Ahmad Vosough, Faramarz Farrahi, Mohamad Ali Sadighi Gilani, Fatemeh Zafarani, Firoozeh Ahmadi   +4 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Mechanistic insights into the Bushen Huatan Huoxue Formula and its components in ameliorating obesity-associated polycystic ovary syndrome

Chinese Medicine
Background Bushen Huatan Huoxue Formula (BHHF), a traditional Chinese medicine decoction, demonstrates potential in treating polycystic ovary syndrome (PCOS), a prevalent endocrine disorder in women of reproductive age that is closely associated with ...
Yu-Xin Jin, Hang-Qi Hu, Jia-Cheng Zhang, Yu-Tian Zhu, Hao-Lin Zhang, Xi-Yan Xin, Rui-Wen Fan, Yang Ye, Yin Li, Dong Li   +9 more
doaj   +1 more source